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Guanming Wu

Associate Professor

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20032022

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  • 2022

    Circulating Neoplastic-Immune Hybrid Cells Predict Metastatic Progression in Uveal Melanoma

    Parappilly, M. S., Chin, Y., Whalen, R. M., Anderson, A. N., Robinson, T. S., Strgar, L., Sutton, T. L., Conley, P., Klocke, C., Gibbs, S. L., Chang, Y. H., Wu, G., Wong, M. H. & Skalet, A. H., Oct 2022, In: Cancers. 14, 19, 4617.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Integrative analysis of drug response and clinical outcome in acute myeloid leukemia

    Bottomly, D., Long, N., Schultz, A. R., Kurtz, S. E., Tognon, C. E., Johnson, K., Abel, M., Agarwal, A., Avaylon, S., Benton, E., Blucher, A., Borate, U., Braun, T. P., Brown, J., Bryant, J., Burke, R., Carlos, A., Chang, B. H., Cho, H. J., Christy, S., & 74 othersCoblentz, C., Cohen, A. M., d'Almeida, A., Cook, R., Danilov, A., Dao, K. H. T., Degnin, M., Dibb, J., Eide, C. A., English, I., Hagler, S., Harrelson, H., Henson, R., Ho, H., Joshi, S. K., Junio, B., Kaempf, A., Kosaka, Y., Laderas, T., Lawhead, M., Lee, H., Leonard, J. T., Lin, C., Lind, E. F., Liu, S. Q., Lo, P., Loriaux, M. M., Luty, S., Maxson, J. E., Macey, T., Martinez, J., Minnier, J., Monteblanco, A., Mori, M., Morrow, Q., Nelson, D., Ramsdill, J., Rofelty, A., Rogers, A., Romine, K. A., Ryabinin, P., Saultz, J. N., Sampson, D. A., Savage, S. L., Schuff, R., Searles, R., Smith, R. L., Spurgeon, S. E., Sweeney, T., Swords, R. T., Thapa, A., Thiel-Klare, K., Traer, E., Wagner, J., Wilmot, B., Wolf, J., Wu, G., Yates, A., Zhang, H., Cogle, C. R., Collins, R. H., Deininger, M. W., Hourigan, C. S., Jordan, C. T., Lin, T. L., Martinez, M. E., Pallapati, R. R., Pollyea, D. A., Pomicter, A. D., Watts, J. M., Weir, S. J., Druker, B. J., McWeeney, S. K. & Tyner, J. W., Aug 8 2022, In: Cancer Cell. 40, 8, p. 850-864.e9

    Research output: Contribution to journal › Article › peer-review

    Open Access
    16 Scopus citations

  • Leveraging biochemical reactions to unravel functional impacts of cancer somatic variants affecting protein interaction interfaces

    Raimondi, F., Wu, G., Burkhart, J. G., Betts, M. J. & Russell, R. B., 2022, In: F1000Research. 10, 1111.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • The reactome pathway knowledgebase 2022

    Gillespie, M., Jassal, B., Stephan, R., Milacic, M., Rothfels, K., Senff-Ribeiro, A., Griss, J., Sevilla, C., Matthews, L., Gong, C., Deng, C., Varusai, T., Ragueneau, E., Haider, Y., May, B., Shamovsky, V., Weiser, J., Brunson, T., Sanati, N., Beckman, L., & 15 othersShao, X., Fabregat, A., Sidiropoulos, K., Murillo, J., Viteri, G., Cook, J., Shorser, S., Bader, G., Demir, E., Sander, C., Haw, R., Wu, G., Stein, L., Hermjakob, H. & D'Eustachio, P., Jan 7 2022, In: Nucleic acids research. 50, D1, p. D687-D692

    Research output: Contribution to journal › Article › peer-review

    Open Access
    241 Scopus citations
  • 2021

    CIDO ontology updates and secondary analysis of host responses to COVID-19 infection based on ImmPort reports and literature

    Huffman, A., Masci, A. M., Zheng, J., Sanati, N., Brunson, T., Wu, G. & He, Y., Dec 2021, In: Journal of Biomedical Semantics. 12, 1, 18.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    6 Scopus citations

  • COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms

    the COVID-19 Disease Map Community, Oct 2021, In: Molecular Systems Biology. 17, 10, e10387.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    26 Scopus citations

  • Leveraging biochemical reactions to unravel functional impacts of cancer somatic variants affecting protein interaction interfaces

    Raimondi, F., Burkhart, J. G., Betts, M. J., Russell, R. B. & Wu, G., 2021, In: F1000Research. 10, p. 1111 1 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Using Reactome to build an autophagy mechanism knowledgebase

    Varusai, T. M., Jupe, S., Sevilla, C., Matthews, L., Gillespie, M., Stein, L., Wu, G., D’Eustachio, P., Metzakopian, E. & Hermjakob, H., 2021, In: Autophagy. 17, 6, p. 1543-1554 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    3 Scopus citations

  • VaximmutorDB: A Web-Based Vaccine Immune Factor Database and Its Application for Understanding Vaccine-Induced Immune Mechanisms

    Berke, K., Sun, P., Ong, E., Sanati, N., Huffman, A., Brunson, T., Loney, F., Ostrow, J., Racz, R., Zhao, B., Xiang, Z., Masci, A. M., Zheng, J., Wu, G. & He, Y., Mar 12 2021, In: Frontiers in immunology. 12, 639491.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    4 Scopus citations
  • 2020

    Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

    PCAWG Drivers and Functional Interpretation Working Group, PCAWG Structural Variation Working Group & PCAWG Consortium, Feb 6 2020, In: Nature. 578, 7793, p. 102-111 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    254 Scopus citations

  • Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

    PCAWG Drivers and Functional Interpretation Group & PCAWG Consortium, Dec 1 2020, In: Communications Biology. 3, 1, 56.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    110 Scopus citations

  • Combined burden and functional impact tests for cancer driver discovery using DriverPower

    PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 734.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    23 Scopus citations

  • Integrative pathway enrichment analysis of multivariate omics data

    PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 735.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    73 Scopus citations

  • Pan-cancer analysis of whole genomes

    The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 6 2020, In: Nature. 578, 7793, p. 82-93 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1165 Scopus citations

  • Pathway and network analysis of more than 2500 whole cancer genomes

    PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 729.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    46 Scopus citations

  • Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

    MC3 Working Group, PCAWG novel somatic mutation calling methods working group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 4748.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    19 Scopus citations

  • Sex differences in oncogenic mutational processes

    PCAWG Tumour Subtypes and Clinical Translation & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 4330.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    40 Scopus citations

  • The reactome pathway knowledgebase

    Jassal, B., Matthews, L., Viteri, G., Gong, C., Lorente, P., Fabregat, A., Sidiropoulos, K., Cook, J., Gillespie, M., Haw, R., Loney, F., May, B., Milacic, M., Rothfels, K., Sevilla, C., Shamovsky, V., Shorser, S., Varusai, T., Weiser, J., Wu, G., & 3 othersStein, L., Hermjakob, H. & D'Eustachio, P., Jan 1 2020, In: Nucleic acids research. 48, D1, p. D498-D503

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1366 Scopus citations
  • 2019

    Acute myeloid leukemia–induced T-cell suppression can be reversed by inhibition of the MAPK pathway

    Moshofsky, K. B., Cho, H. J., Wu, G., Romine, K. A., Newman, M. T., Kosaka, Y., McWeeney, S. K. & Lind, E. F., Oct 22 2019, In: Blood Advances. 3, 20, p. 3038-3051 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • Natural product target network reveals potential for cancer combination therapies

    Chamberlin, S. R., Blucher, A., Wu, G., Shinto, L., Choonoo, G., Kulesz-Martin, M. & McWeeney, S., 2019, In: Frontiers in Pharmacology. 10, MAY, 557.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    36 Scopus citations

  • Reactome and ORCID-fine-grained credit attribution for community curation

    Viteri, G., Matthews, L., Varusai, T., Gillespie, M., Milacic, M., Cook, J., Weiser, J., Shorser, S., Sidiropoulos, K., Fabregat, A., Haw, R., Wu, G., Stein, L., D'Eustachio, P. & Hermjakob, H., Jan 1 2019, In: Database : the journal of biological databases and curation. 2019

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • VIO: Ontology classification and study of vaccine responses given various experimental and analytical conditions

    Ong, E., Sun, P., Berke, K., Zheng, J., Wu, G. & He, Y., Dec 23 2019, In: BMC bioinformatics. 20, 704.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations
  • 2018

    Automation of ReactomeFIViz via CyREST API

    Wu, G. & Loney, F., 2018, In: F1000Research. 7, 531.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • Network-based predictors of progression in head and neck squamous cell carcinoma

    Sanati, N., Iancu, O. D., Wu, G., Jacobs, J. E. & McWeeney, S. K., May 29 2018, In: Frontiers in Genetics. 9, MAY, 183.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    17 Scopus citations

  • Reactome graph database: Efficient access to complex pathway data

    Fabregat, A., Korninger, F., Viteri, G., Sidiropoulos, K., Marin-Garcia, P., Ping, P., Wu, G., Stein, L., D’Eustachio, P. & Hermjakob, H., Jan 2018, In: PLoS computational biology. 14, 1, e1005968.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    132 Scopus citations

  • The Reactome Pathway Knowledgebase

    Fabregat, A., Jupe, S., Matthews, L., Sidiropoulos, K., Gillespie, M., Garapati, P., Haw, R., Jassal, B., Korninger, F., May, B., Milacic, M., Roca, C. D., Rothfels, K., Sevilla, C., Shamovsky, V., Shorser, S., Varusai, T., Viteri, G., Weiser, J., Wu, G., & 3 othersStein, L., Hermjakob, H. & D'Eustachio, P., Jan 1 2018, In: Nucleic acids research. 46, D1, p. D649-D655

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1559 Scopus citations
  • 2017

    Comprehensive definition of human immunodominant CD8 antigens in tuberculosis

    Lewinsohn, D. A., Swarbrick, G. M., Park, B., Cansler, M. E., Null, M. D., Toren, K. G., Baseke, J., Zalwango, S., Mayanja-Kizza, H., Malone, L. L., Nyendak, M., Wu, G., Guinn, K., McWeeney, S., Mori, T., Chervenak, K. A., Sherman, D. R., Boom, W. H. & Lewinsohn, D. M., Dec 1 2017, In: npj Vaccines. 2, 1, 8.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations

  • Plant Reactome: A resource for plant pathways and comparative analysis

    Naithani, S., Preece, J., D'Eustachio, P., Gupta, P., Amarasinghe, V., Dharmawardhana, P. D., Wu, G., Fabregat, A., Elser, J. L., Weiser, J., Keays, M., Fuentes, A. M. P., Petryszak, R., Stein, L. D., Ware, D. & Jaiswal, P., Jan 1 2017, In: Nucleic acids research. 45, D1, p. D1029-D1039

    Research output: Contribution to journal › Article › peer-review

    Open Access
    46 Scopus citations
  • 2016

    Reactome from a WikiPathways Perspective

    Bohler, A., Wu, G., Kutmon, M., Pradhana, L. A., Coort, S. L., Hanspers, K., Haw, R., Pico, A. R. & Evelo, C. T., May 2016, In: PLoS computational biology. 12, 5, e1004941.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    28 Scopus citations

  • The reactome pathway knowledgebase

    Fabregat, A., Sidiropoulos, K., Garapati, P., Gillespie, M., Hausmann, K., Haw, R., Jassal, B., Jupe, S., Korninger, F., McKay, S., Matthews, L., May, B., Milacic, M., Rothfels, K., Shamovsky, V., Webber, M., Weiser, J., Williams, M., Wu, G., Stein, L., & 2 othersHermjakob, H. & D'Eustachio, P., 2016, In: Nucleic acids research. 44, D1, p. D481-D487

    Research output: Contribution to journal › Article › peer-review

    Open Access
    722 Scopus citations
  • 2015

    Between pathways and networks lies context: Implications for precision medicine

    Laderas, T., Wu, G. & McWeeney, S., Sep 1 2015, In: Science Progress. 98, 3, p. 253-263 11 p.

    Research output: Contribution to journal › Article › peer-review

  • Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction

    Zhang, S., Chung, W. C., Wu, G., Egan, S. E., Miele, L. & Xu, K., May 15 2015, In: Cancer Research. 75, 10, p. 1936-1943 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    42 Scopus citations
  • 2014

    A controlled vocabulary for pathway entities and events

    Jupe, S., Jassal, B., Williams, M. & Wu, G., 2014, In: Database. 2014

    Research output: Contribution to journal › Article › peer-review

    8 Scopus citations

  • Gramene 2013: Comparative plant genomics resources

    Monaco, M. K., Stein, J., Naithani, S., Wei, S., Dharmawardhana, P., Kumari, S., Amarasinghe, V., Youens-Clark, K., Thomason, J., Preece, J., Pasternak, S., Olson, A., Jiao, Y., Lu, Z., Bolser, D., Kerhornou, A., Staines, D., Walts, B., Wu, G., D'Eustachio, P., & 6 othersHaw, R., Croft, D., Kersey, P. J., Stein, L., Jaiswal, P. & Ware, D., Jan 1 2014, In: Nucleic acids research. 42, D1, p. D1193-D1199

    Research output: Contribution to journal › Article › peer-review

    Open Access
    143 Scopus citations

  • Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

    The MAGIC investigators & The GIANT consortium, Aug 7 2014, In: PLoS genetics. 10, 8, e1004517.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    156 Scopus citations

  • ReactomeFIViz: A cytoscape app for pathway and network-based data analysis

    Wu, G., Dawson, E., Duong, A., Haw, R. & Stein, L., Sep 12 2014, In: F1000Research. 3, 4431.2.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    160 Scopus citations

  • The Reactome pathway knowledgebase

    Croft, D., Mundo, A. F., Haw, R., Milacic, M., Weiser, J., Wu, G., Caudy, M., Garapati, P., Gillespie, M., Kamdar, M. R., Jassal, B., Jupe, S., Matthews, L., May, B., Palatnik, S., Rothfels, K., Shamovsky, V., Song, H., Williams, M., Birney, E., & 3 othersHermjakob, H., Stein, L. & D'Eustachio, P., Jan 1 2014, In: Nucleic acids research. 42, D1, p. D472-D477

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1187 Scopus citations

  • Tumor-suppressive activity of lunatic fringe in prostate through differential modulation of notch receptor activation

    Zhang, S., Chung, W. C., Wu, G., Egan, S. E. & Xu, K., Feb 2014, In: Neoplasia (United States). 16, 2, p. 158-167 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations
  • 2013

    Systematic MicroRNA Analysis Identifies ATP6V0C as an Essential Host Factor for Human Cytomegalovirus Replication

    Pavelin, J., Reynolds, N., Chiweshe, S., Wu, G., Tiribassi, R. & Grey, F., 2013, In: PLoS pathogens. 9, 12, p. 1-13 13 p., e1003820.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    35 Scopus citations
  • 2012

    A genome-wide association search for type 2 diabetes genes in african americans

    DIAGRAM Consortium, MAGIC Investigators, Anders Hamsten on behalf of Procardis Consortium, DIAGRAM Consortium, GIANT Consortium, Global BPgen Consortium & for the MAGIC investigators, Jan 4 2012, In: PloS one. 7, 1, e29202.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    138 Scopus citations

  • A network module-based method for identifying cancer prognostic signatures

    Wu, G. & Stein, L., 2012, In: Genome biology. 13, 12, p. R112

    Research output: Contribution to journal › Article › peer-review

    Open Access
    43 Scopus citations

  • Annotating cancer variants and anti-cancer therapeutics in Reactome

    Milacic, M., Haw, R., Rothfels, K., Wu, G., Croft, D., Hermjakob, H., D'Eustachio, P. & Stein, L., Dec 2012, In: Cancers. 4, 4, p. 1180-1211 32 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    227 Scopus citations

  • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals

    Dastani, Z., Hivert, M. F., Timpson, N. J., Perry, J. R. B., Yuan, X., Scott, R. A., Henneman, P., Heid, I. M., Kizer, J. R., Lyytikäinen, L. P., Fuchsberger, C., Tanaka, T., Morris, A. P., Small, K., Isaacs, A., Beekman, M., Coassin, S., Lohman, K., Qi, L., Kanoni, S., & 523 othersPankow, J. S., Uh, H. W., Wu, Y., Bidulescu, A., Rasmussen-Torvik, L. J., Greenwood, C. M. T., Ladouceur, M., Grimsby, J., Manning, A. K., Liu, C. T., Kooner, J., Mooser, V. E., Vollenweider, P., Kapur, K. A., Chambers, J., Wareham, N. J., Langenberg, C., Frants, R., Willems-VanDijk, K., Oostra, B. A., Willems, S. M., Lamina, C., Winkler, T. W., Psaty, B. M., Tracy, R. P., Brody, J., Chen, I., Viikari, J., Kähönen, M., Pramstaller, P. P., Evans, D. M., St. Pourcain, B., Sattar, N., Wood, A. R., Bandinelli, S., Carlson, O. D., Egan, J. M., Böhringer, S., van Heemst, D., Kedenko, L., Kristiansson, K., Nuotio, M. L., Loo, B. M., Harris, T., Garcia, M., Kanaya, A., Haun, M., Klopp, N., Wichmann, H. E., Deloukas, P., Katsareli, E., Couper, D. J., Duncan, B. B., Kloppenburg, M., Adair, L. S., Borja, J. B., Florez, J. C., MAGIC Consortium, C., GLGC Investigators, I., MuTHER Consortium, C., Wilson, J. G., Musani, S., Guo, X., Johnson, T., Semple, R., Teslovich, T. M., Redline, S., Buxbaum, S. G., Mohlke, K. L., Meulenbelt, I., Ballantyne, C. M., Dedoussis, G. V., Hu, F. B., Liu, Y., Paulweber, B., Spector, T. D., Slagboom, P. E., Ferrucci, L., Jula, A., Perola, M., Raitakari, O., Salomaa, V., Eriksson, J. G., Frayling, T. M., Hicks, A. A., Lehtimäki, T., Smith, G. D., Siscovick, D. S., Kronenberg, F., van Duijn, C., Loos, R. J. F., Waterworth, D. M., Meigs, J. B., Dupuis, J., Richards, J. B., Voight, B. F., Scott, L. J., Steinthorsdottir, V., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Hofmann, O. M., Segrè, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Boström, K. B., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Fox, C. S., Franklin, C. S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Isomaa, B., Jackson, A. U., Johnson, P. R. V., Jørgensen, T., Kao, W. H. L., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M. A., Narisu, N., Nilsson, P., Owen, K. R., Payne, F., Petersen, A. K., Platou, C., Proenca, C., Prokopenko, I., Rathmann, W., Rayner, N. W., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparsø, T., Strassburger, K., Stringham, H. M., Sun, Q., Swift, A. J., Thorand, B., Tichet, J., Tuomi, T., van Dam, R. M., van Haeften, T. W., van Herpt, T., van Vliet-Ostaptchouk, J. V., Walters, G. B., Weedon, M. N., Wijmenga, C., Witteman, J., Bergman, R. N., Cauchi, S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hofman, A., Hunter, D. J., Hveem, K., Laakso, M., Morris, A. D., Palmer, C. N. A., Rudan, I., Sijbrands, E., Stein, L. D., Tuomilehto, J., Uitterlinden, A., Walker, M., Watanabe, R. M., Abecasis, G. R., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Pedersen, O., Barroso, I., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J. F., Illig, T., Froguel, P., Stefansson, K., Altshuler, D., Boehnke, M., McCarthy, M. I., David, T., Soranzo, N., Wheeler, E., Glazer, N. L., Bouatia-Naji, N., Mägi, R., Randall, J., Elliott, P., Rybin, D., Dehghan, A., Hottenga, J. J., Goel, A., Lajunen, T., Doney, A., Cavalcanti-Proença, C., Kumari, M., Zabena, C., Ingelsson, E., An, P., O'Connell, J., Luan, J., Elliott, A., Roccasecca, R. M., Pattou, F., Sethupathy, P., Ariyurek, Y., Barter, P., Beilby, J. P., Ben-Shlomo, Y., Bergmann, S., Bochud, M., Bonnefond, A., Borch-Johnsen, K., Böttcher, Y., Brunner, E., Bumpstead, S. J., Chen, Y. D. I., Chines, P., Clarke, R., Coin, L. J. M., Cooper, M. N., Song, K., Day, I. N. M., de Geus, E. J. C., Delplanque, J., Fedson, A. C., Fischer-Rosinsky, A., Forouhi, N. G., Franzosi, M. G., Galan, P., Goodarzi, M. O., Graessler, J., Grundy, S., Gwilliam, R., Hallmans, G., Hammond, N., Han, X., Hartikainen, A. L., Hayward, C., Heath, S. C., Hercberg, S., Hillman, D. R., Hingorani, A. D., Hui, J., Hung, J., Kaakinen, M., Kaprio, J., Kesaniemi, Y. A., Kivimaki, M., Knight, B., Koskinen, S., Kovacs, P., Kyvik, K. O., Lathrop, GM., Lawlor, D. A., Bacquer, O. L., Lecoeur, C., Li, Y., Mahley, R., Mangino, M., Martínez-Larrad, M. 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    Research output: Contribution to journal › Article › peer-review

    Open Access
    351 Scopus citations
  • 2011

    Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1

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    Research output: Contribution to journal › Article › peer-review

    Open Access
    149 Scopus citations

  • Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

    Strawbridge, R. J., Dupuis, J., Prokopenko, I., Barker, A., Ahlqvist, E., Rybin, D., Petrie, J. R., Travers, M. E., Bouatia-Naji, N., Dimas, A. S., Nica, A. C., Wheeler, E., Chen, H., Voight, B. F., Taneera, J., Kanoni, S., Peden, J. F., Turrini, F., Gustafsson, S., Zabena, C., & 671 othersAlmgren, P., Barker, D. J. P., Barnes, D., Dennison, E. M., Eriksson, J. G., Eriksson, P., Eury, E., Folkersen, L., Fox, C. S., Frayling, T. M., Goel, A., Gu, H. F., Horikoshi, M., Isomaa, B., Jackson, A. U., Jameson, K. A., Kajantie, E., Kerr-Conte, J., Kuulasmaa, T., Kuusisto, J., Loos, R. J. F., Luan, J., Makrilakis, K., Manning, A. K., Martínez-Larrad, M. T., Narisu, N., Mannila, M. N., Öhrvik, J., Osmond, C., Pascoe, L., Payne, F., Sayer, A. A., Sennblad, B., Silveira, A., Stančcáková, A., Stirrups, K., Swift, A. J., Syvänen, A. C., Tuomi, T., Van't Hooft, F. M., Walker, M., Weedon, M. N., Xie, W., Zethelius, B., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. 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    Research output: Contribution to journal › Article › peer-review

    Open Access
    142 Scopus citations

  • Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening

    Sawey, E. T., Chanrion, M., Cai, C., Wu, G., Zhang, J., Zender, L., Zhao, A., Busuttil, R. W., Yee, H., Stein, L., French, D. M., Finn, R. S., Lowe, S. W. & Powers, S., Mar 8 2011, In: Cancer Cell. 19, 3, p. 347-358 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    336 Scopus citations

  • Reactome: A database of reactions, pathways and biological processes

    Croft, D., O'Kelly, G., Wu, G., Haw, R., Gillespie, M., Matthews, L., Caudy, M., Garapati, P., Gopinath, G., Jassal, B., Jupe, S., Kalatskaya, I., MayMahajan, S., May, B., Ndegwa, N., Schmidt, E., Shamovsky, V., Yung, C., Birney, E., Hermjakob, H., & 2 othersD'Eustachio, P. & Stein, L., Jan 2011, In: Nucleic acids research. 39, SUPPL. 1, p. D691-D697

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1157 Scopus citations
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    A human functional protein interaction network and its application to cancer data analysis

    Wu, G., Feng, X. & Stein, L., May 19 2010, In: Genome biology. 11, 5, R53.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    484 Scopus citations

  • A viral microRNA down-regulates multiple cell cycle genes through mRNA 59′UTRs

    Grey, F., Tirabassi, R., Meyers, H., Wu, G., McWeeney, S., Hook, L. & Nelson, J., Jun 2010, In: PLoS pathogens. 6, 6

    Research output: Contribution to journal › Article › peer-review

    Open Access
    174 Scopus citations

  • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Hofmann, O. M., & 138 othersDupuis, J., Qi, L., Segrè, A. V., Van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Boström, K. B., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Fox, C. S., Franklin, C. S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Isomaa, B., Jackson, A. U., Johnson, P. R. V., Jørgensen, T., Kao, W. H. L., Klopp, N., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M. A., Narisu, N., Nilsson, P., Owen, K. R., Payne, F., Perry, J. R. B., Petersen, A. K., Platou, C., Proença, C., Prokopenko, I., Rathmann, W., Rayner, N. W., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparsø, T., Strassburger, K., Stringham, H. M., Sun, Q., Swift, A. J., Thorand, B., Tichet, J., Tuomi, T., Van Dam, R. M., Van Haeften, T. W., Van Herpt, T., Van Vliet-Ostaptchouk, J. V., Walters, G. B., Weedon, M. N., Wijmenga, C., Witteman, J., Bergman, R. N., Cauchi, S., Collins, F. S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hofman, A., Hunter, D. J., Hveem, K., Laakso, M., Mohlke, K. L., Morris, A. D., Palmer, C. N. A., Pramstaller, P. P., Rudan, I., Sijbrands, E., Stein, L. D., Tuomilehto, J., Uitterlinden, A., Walker, M., Wareham, N. J., Watanabe, R. M., Abecasis, G. R., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Hu, F. B., Meigs, J. B., Pankow, J. S., Pedersen, O., Wichmann, H. E., Barroso, I., Florez, J. C., Frayling, T. M., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J. F., Illig, T., Froguel, P., Van Duijn, C. M., Stefansson, K., Altshuler, D., Boehnke, M. & McCarthy, M. I., Jul 2010, In: Nature genetics. 42, 7, p. 579-589 11 p.

    Research output: Contribution to journal › Article › peer-review

    868 Scopus citations