ETHANOL WITHDRAWAL QTLS AND CANDIDATE GENES

  • Buck, Kari (PI)

Project: Research project

Project Details

Description

DESCRIPTION: Decreased GABAergic transmission is thought to play an important role in the development of alcohol dependence/withdrawal, but the specific genes responsible for adaptive changes in GABAergic transmission remain to be elucidated. In our studies to date, QTL analysis using three populations derived from the C57BL/6J and DBA/2J inbred mouse strains have identified several loci that contribute to genetic differences in acute alcohol withdrawal severity. One alcohol withdrawal locus (Alcw1) has been localized at a high level of significance (p
StatusFinished
Effective start/end date8/1/971/31/21

Funding

  • National Institutes of Health: $343,035.00
  • National Institutes of Health: $346,500.00
  • National Institutes of Health: $260,252.00
  • National Institutes of Health: $107,279.00
  • National Institutes of Health: $50,961.00
  • National Institutes of Health: $329,725.00
  • National Institutes of Health: $76,218.00
  • National Institutes of Health: $346,500.00
  • National Institutes of Health: $100,836.00
  • National Institutes of Health: $283,500.00
  • National Institutes of Health: $329,725.00
  • National Institutes of Health: $125,477.00
  • National Institutes of Health: $264,250.00
  • National Institutes of Health: $264,250.00

ASJC

  • Medicine(all)

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