3D computer modeling of human cardiogenesis

Jeffrey O. Pentecost; Jose Icardo; Kent L. Thornburg

doi:10.1016/S0895-6111(98)00063-9

3D computer modeling of human cardiogenesis

Jeffrey O. Pentecost
, Jose Icardo
, Kent L. Thornburg

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

We obtained digitized histological serial sections of three human embryos of different stages from the Armed Forces Institute of Pathology from which contours of cardiac structures were digitally traced. Traces were placed in register for the construction of wire frame models using Silicon Graphics Incorporated 3D computer modeling software (Alias/Wavefront) and for surface rendering to demonstrate internal and external developmental anatomy. The models allowed stage-to-stage morphing and physical model construction using stereolithography. These innovations in embryo reconstruction not only facilitate medical education, they also serve as new tools for scientific investigation of cardiogenesis and congenital heart disease.

Original language	English (US)
Pages (from-to)	45-49
Number of pages	5
Journal	Computerized Medical Imaging and Graphics
Volume	23
Issue number	1
DOIs	https://doi.org/10.1016/S0895-6111(98)00063-9
State	Published - Jan 1999

Funding

This project is supported in part by a grant from the Biomedical Information Communication Center at Oregon Health Sciences University, and from Lewis and Clark Chapter of the March of Dimes. We thank Mike Perkins of Lockheed Martin, Inc. for help with model construction, Mark Forsythe of Acuity, Inc. for technical advice and Rick Verbeck from Silicon Graphics, Inc., for various forms of helpful advice.

Funders
Biomedical Information and Communication Center
March of Dimes Foundation
Oregon Health Sciences University Oregon Regional Primate Research Center

Keywords

Cardiogenesis
Embryo
Heart
Human
Modeling
Morphing
Stereolithography

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging
Computer Vision and Pattern Recognition
Health Informatics
Computer Graphics and Computer-Aided Design

Access to Document

10.1016/S0895-6111(98)00063-9

Cite this

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title = "3D computer modeling of human cardiogenesis",

abstract = "We obtained digitized histological serial sections of three human embryos of different stages from the Armed Forces Institute of Pathology from which contours of cardiac structures were digitally traced. Traces were placed in register for the construction of wire frame models using Silicon Graphics Incorporated 3D computer modeling software (Alias/Wavefront) and for surface rendering to demonstrate internal and external developmental anatomy. The models allowed stage-to-stage morphing and physical model construction using stereolithography. These innovations in embryo reconstruction not only facilitate medical education, they also serve as new tools for scientific investigation of cardiogenesis and congenital heart disease.",

keywords = "Cardiogenesis, Embryo, Heart, Human, Modeling, Morphing, Stereolithography",

author = "Pentecost, \{Jeffrey O.\} and Jose Icardo and Thornburg, \{Kent L.\}",

note = "Funding Information: This project is supported in part by a grant from the Biomedical Information Communication Center at Oregon Health Sciences University, and from Lewis and Clark Chapter of the March of Dimes. We thank Mike Perkins of Lockheed Martin, Inc. for help with model construction, Mark Forsythe of Acuity, Inc. for technical advice and Rick Verbeck from Silicon Graphics, Inc., for various forms of helpful advice. ",

year = "1999",

month = jan,

doi = "10.1016/S0895-6111(98)00063-9",

language = "English (US)",

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journal = "Computerized Medical Imaging and Graphics",

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T1 - 3D computer modeling of human cardiogenesis

AU - Pentecost, Jeffrey O.

AU - Icardo, Jose

AU - Thornburg, Kent L.

N1 - Funding Information: This project is supported in part by a grant from the Biomedical Information Communication Center at Oregon Health Sciences University, and from Lewis and Clark Chapter of the March of Dimes. We thank Mike Perkins of Lockheed Martin, Inc. for help with model construction, Mark Forsythe of Acuity, Inc. for technical advice and Rick Verbeck from Silicon Graphics, Inc., for various forms of helpful advice.

PY - 1999/1

Y1 - 1999/1

N2 - We obtained digitized histological serial sections of three human embryos of different stages from the Armed Forces Institute of Pathology from which contours of cardiac structures were digitally traced. Traces were placed in register for the construction of wire frame models using Silicon Graphics Incorporated 3D computer modeling software (Alias/Wavefront) and for surface rendering to demonstrate internal and external developmental anatomy. The models allowed stage-to-stage morphing and physical model construction using stereolithography. These innovations in embryo reconstruction not only facilitate medical education, they also serve as new tools for scientific investigation of cardiogenesis and congenital heart disease.

AB - We obtained digitized histological serial sections of three human embryos of different stages from the Armed Forces Institute of Pathology from which contours of cardiac structures were digitally traced. Traces were placed in register for the construction of wire frame models using Silicon Graphics Incorporated 3D computer modeling software (Alias/Wavefront) and for surface rendering to demonstrate internal and external developmental anatomy. The models allowed stage-to-stage morphing and physical model construction using stereolithography. These innovations in embryo reconstruction not only facilitate medical education, they also serve as new tools for scientific investigation of cardiogenesis and congenital heart disease.

KW - Cardiogenesis

KW - Embryo

KW - Heart

KW - Human

KW - Modeling

KW - Morphing

KW - Stereolithography

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JO - Computerized Medical Imaging and Graphics

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3D computer modeling of human cardiogenesis

Abstract

Funding

Keywords

ASJC Scopus subject areas

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