TY - JOUR
T1 - A diagnostic delay of 5 hours increases the risk of death after blunt hollow viscus injury
AU - Malinoski, Darren J.
AU - Patel, Madhukar S.
AU - Yakar, Didem Oncel
AU - Green, Donald
AU - Qureshi, Faisal
AU - Inaba, Kenji
AU - Brown, Carlos V.R.
AU - Salim, Ali
PY - 2010/7
Y1 - 2010/7
N2 - Background: Hollow viscus injuries (HVI) are uncommon after blunt trauma, and accomplishing a timely diagnosis can be difficult. Time to operative intervention has been implicated as a risk factor for mortality, but reports are conflicting. Methods: All blunt trauma admissions to an academic level 1 trauma center from January 1992 to September 2005 were retrospectively reviewed. Patients with a diagnosis of blunt HVI were included. Patients who died within 24 hours were excluded. Data regarding patient demographics, injuries, time from admission until laparotomy, length of stay, and mortality were recorded, and a multivariate analysis to determine independent risk factors for mortality was carried out. A p < 0.05 was considered significant. Results: Of 35,033 blunt trauma admissions, there were 195 (0.6%) HVI patients with the following characteristics (data expressed as mean ± 1 SD): mean age of 35 years ± 16 years, Injury Severity Score of 17 ± 11, time from admission to laparotomy of 5.9 hours ± 5.8 hours, operative blood loss of 1500 mL ± 1800 mL, and length of stay of 19 days ± 23 days. Twelve percent presented with a systolic pressure <90 mm Hg and 9% died. Independent risk factors for mortality were age (odds ratio [OR] = 1.04, p = 0.005), Abdominal Abbreviated Injury Score (OR = 2.5, p = 0.011), the presence of a significant extra-abdominal injury (OR = 3.4, p = 0.043), and a delay of more than 5 hours between admission and laparotomy (OR = 3.2, p = 0.0499). Eighty-six percent of the deaths in patients who had a delay of >5 hours were because of abdominal-related sepsis. Conclusion: HVI occurred in less than 1% of all blunt trauma admissions. Delays in operative intervention are associated with an increased mortality. A high index of suspicion is needed to make a timely diagnosis and minimize risk.
AB - Background: Hollow viscus injuries (HVI) are uncommon after blunt trauma, and accomplishing a timely diagnosis can be difficult. Time to operative intervention has been implicated as a risk factor for mortality, but reports are conflicting. Methods: All blunt trauma admissions to an academic level 1 trauma center from January 1992 to September 2005 were retrospectively reviewed. Patients with a diagnosis of blunt HVI were included. Patients who died within 24 hours were excluded. Data regarding patient demographics, injuries, time from admission until laparotomy, length of stay, and mortality were recorded, and a multivariate analysis to determine independent risk factors for mortality was carried out. A p < 0.05 was considered significant. Results: Of 35,033 blunt trauma admissions, there were 195 (0.6%) HVI patients with the following characteristics (data expressed as mean ± 1 SD): mean age of 35 years ± 16 years, Injury Severity Score of 17 ± 11, time from admission to laparotomy of 5.9 hours ± 5.8 hours, operative blood loss of 1500 mL ± 1800 mL, and length of stay of 19 days ± 23 days. Twelve percent presented with a systolic pressure <90 mm Hg and 9% died. Independent risk factors for mortality were age (odds ratio [OR] = 1.04, p = 0.005), Abdominal Abbreviated Injury Score (OR = 2.5, p = 0.011), the presence of a significant extra-abdominal injury (OR = 3.4, p = 0.043), and a delay of more than 5 hours between admission and laparotomy (OR = 3.2, p = 0.0499). Eighty-six percent of the deaths in patients who had a delay of >5 hours were because of abdominal-related sepsis. Conclusion: HVI occurred in less than 1% of all blunt trauma admissions. Delays in operative intervention are associated with an increased mortality. A high index of suspicion is needed to make a timely diagnosis and minimize risk.
KW - Blunt hollow viscus injury
KW - Diagnostic delay
KW - Laparotomy
KW - Mortality
UR - http://www.scopus.com/inward/record.url?scp=77954737032&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77954737032&partnerID=8YFLogxK
U2 - 10.1097/TA.0b013e3181db37f5
DO - 10.1097/TA.0b013e3181db37f5
M3 - Article
C2 - 20622582
AN - SCOPUS:77954737032
SN - 2163-0755
VL - 69
SP - 84
EP - 87
JO - Journal of Trauma and Acute Care Surgery
JF - Journal of Trauma and Acute Care Surgery
IS - 1
ER -