TY - JOUR
T1 - A Geodesics-Based Surface Parameterization to Assess Aneurysm Progression
AU - Phan, Ly
AU - Courchaine, Katherine
AU - Azarbal, Amir
AU - Vorp, David
AU - Grimm, Cindy
AU - Rugonyi, Sandra
N1 - Funding Information:
This work has been partly supported by Grant Nos. NSF DBI-1052688 (Rugonyi), NIH R01HL094570 (Rugonyi), NSF DEB-1053554 (Grimm), and NSF DBI-1053171 (Grimm).
Publisher Copyright:
© 2016 by ASME.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - Abdominal aortic aneurysm (AAA) intervention and surveillance is currently based on maximum transverse diameter, even though it is recognized that this might not be the best strategy. About 10% of patients with small AAA transverse diameters, for whom intervention is not considered, still rupture; while patients with large AAA transverse diameters, for whom intervention would have been recommended, have stable aneurysms that do not rupture. While maximum transverse diameter is easy to measure and track in clinical practice, one of its main drawbacks is that it does not represent the whole AAA and rupture seldom occurs in the region of maximum transverse diameter. By following maximum transverse diameter alone clinicians are missing information on the shape change dynamics of the AAA, and clues that could lead to better patient care. We propose here a method to register AAA surfaces that were obtained from the same patient at different time points. Our registration method could be used to track the local changes of the patient-specific AAA. To achieve registration, our procedure uses a consistent parameterization of the AAA surfaces followed by strain relaxation. The main assumption of our procedure is that growth of the AAA occurs in such a way that surface strains are smoothly distributed, while regions of small and large surface growth can be differentiated. The proposed methodology has the potential to unravel different patterns of AAA growth that could be used to stratify patient risks.
AB - Abdominal aortic aneurysm (AAA) intervention and surveillance is currently based on maximum transverse diameter, even though it is recognized that this might not be the best strategy. About 10% of patients with small AAA transverse diameters, for whom intervention is not considered, still rupture; while patients with large AAA transverse diameters, for whom intervention would have been recommended, have stable aneurysms that do not rupture. While maximum transverse diameter is easy to measure and track in clinical practice, one of its main drawbacks is that it does not represent the whole AAA and rupture seldom occurs in the region of maximum transverse diameter. By following maximum transverse diameter alone clinicians are missing information on the shape change dynamics of the AAA, and clues that could lead to better patient care. We propose here a method to register AAA surfaces that were obtained from the same patient at different time points. Our registration method could be used to track the local changes of the patient-specific AAA. To achieve registration, our procedure uses a consistent parameterization of the AAA surfaces followed by strain relaxation. The main assumption of our procedure is that growth of the AAA occurs in such a way that surface strains are smoothly distributed, while regions of small and large surface growth can be differentiated. The proposed methodology has the potential to unravel different patterns of AAA growth that could be used to stratify patient risks.
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U2 - 10.1115/1.4033082
DO - 10.1115/1.4033082
M3 - Article
C2 - 27003915
AN - SCOPUS:84971311493
SN - 0148-0731
VL - 138
JO - Journal of Biomechanical Engineering
JF - Journal of Biomechanical Engineering
IS - 5
M1 - 054503
ER -