Abstract
Epigenetic modification of chromatin has been proposed to translate environmental stimuli into persistent "cellular memories." Recent studies suggest that epigenetic pathways regulate long-term behavioral adaptation in the nervous system. In this issue of Neuron, Renthal et al. utilize genetic manipulations of HDAC5 to provide strong evidence for a role for histone acetylation in the behavioral response to cocaine.
Original language | English (US) |
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Pages (from-to) | 415-417 |
Number of pages | 3 |
Journal | Neuron |
Volume | 56 |
Issue number | 3 |
DOIs | |
State | Published - Nov 8 2007 |
ASJC Scopus subject areas
- General Neuroscience