Abstract
Background: A four-site RCT of Fatigue: Take Control (FTC), a multicomponent group program, found no significant differences from a control program, MS: Take Control (MSTC), in fatigue on the Modified Fatigue Impact Scale (MFIS) through 6 months. Objective: Assess FTC for a delayed effect on fatigue. Methods: Of 78 subjects at one site, 74 randomized to FTC or MSTC completed the MFIS at 12 months. Results: Compared to baseline, FTC produced greater improvements in MFIS scores than MSTC (FTC −8.9 (confidence interval (CI): 32.2, 45), MSTC −2.5 (CI 39.6, 47.7), p = 0.03) at 12 months. Conclusion: The delayed effect of FTC on fatigue suggests the need for longer follow-up when assessing interventions for fatigue.
Original language | English (US) |
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Pages (from-to) | 871-875 |
Number of pages | 5 |
Journal | Multiple Sclerosis Journal |
Volume | 25 |
Issue number | 6 |
DOIs | |
State | Published - May 1 2019 |
Keywords
- Multiple sclerosis
- clinical trial
- fatigue
- rehabilitation
- self-care
- symptom management
ASJC Scopus subject areas
- Neurology
- Clinical Neurology