A reference cross DNA panel for zebrafish (Danio rerio) anchored with simple sequence length polymorphisms

Ela W. Knapik; Alec Goodman; O. Scott Atkinson; Carole T. Roberts; Masahide Shiozawa; Chäng U. Sim; Sarah Weksler-Zangen; Maria R. Trolliet; Corey Futrell; Brendan A. Innes; George Koike; Michael G. McLaughlin; Luc Pierre; Jason S. Simon; Eduardo Vilallonga; Millie Roy; Pei Wen Chiang; Mark C. Fishman; Wolfgang Driever; Howard J. Jacob

A reference cross DNA panel for zebrafish (Danio rerio) anchored with simple sequence length polymorphisms

Ela W. Knapik, Alec Goodman, O. Scott Atkinson, Carole T. Roberts, Masahide Shiozawa, Chäng U. Sim, Sarah Weksler-Zangen, Maria R. Trolliet, Corey Futrell, Brendan A. Innes, George Koike, Michael G. McLaughlin, Luc Pierre, Jason S. Simon, Eduardo Vilallonga, Millie Roy, Pei Wen Chiang, Mark C. Fishman, Wolfgang Driever, Howard J. Jacob

Research output: Contribution to journal › Article › peer-review

153 Scopus citations

Abstract

The ultimate informativeness of the zebrafish mutations described in this issue will rest in part on the ability to clone these genes. However, the genetic infrastructure required for the positional cloning in zebrafish is still in its infancy. Here we report a reference cross panel of DNA, consisting of 520 F₂ progeny (1040 meioses) that has been anchored to a zebrafish genetic linkage map by 102 simple sequence length polymorphisms. This reference cross DNA provides: (1) a panel of DNA from the cross that was used to construct the genetic linkage map, upon which polymorphic gene(s) and genetic markers can be mapped; (2) a fine order mapping tool, with a maximum resolution of 0.1 cM; and (3) a foundation for the development of a physical map (an ordered array of clones each containing a known portion of the genome). This reference cross DNA will serve as a resource enabling investigators to relate genes or genetic markers directly to a single genetic linkage map and avoid the problem of integrating different maps with different genetic markers, as must be currently done when using randomly amplified polymorphic DNA markers, or as has occurred with human genetic linkage maps.

Original language	English (US)
Pages (from-to)	451-460
Number of pages	10
Journal	Development
Volume	123
State	Published - 1996
Externally published	Yes

Keywords

Genetic map
Reference cross
Zebrafish

ASJC Scopus subject areas

Molecular Biology
Developmental Biology

Cite this

Knapik, E. W., Goodman, A., Scott Atkinson, O., Roberts, C. T., Shiozawa, M., Sim, C. U., Weksler-Zangen, S., Trolliet, M. R., Futrell, C., Innes, B. A., Koike, G., McLaughlin, M. G., Pierre, L., Simon, J. S., Vilallonga, E., Roy, M., Chiang, P. W., Fishman, M. C., Driever, W., & Jacob, H. J. (1996). A reference cross DNA panel for zebrafish (Danio rerio) anchored with simple sequence length polymorphisms. Development, 123, 451-460.

Knapik, EW, Goodman, A, Scott Atkinson, O, Roberts, CT, Shiozawa, M, Sim, CU, Weksler-Zangen, S, Trolliet, MR, Futrell, C, Innes, BA, Koike, G, McLaughlin, MG, Pierre, L, Simon, JS, Vilallonga, E, Roy, M, Chiang, PW, Fishman, MC, Driever, W & Jacob, HJ 1996, 'A reference cross DNA panel for zebrafish (Danio rerio) anchored with simple sequence length polymorphisms', Development, vol. 123, pp. 451-460.

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abstract = "The ultimate informativeness of the zebrafish mutations described in this issue will rest in part on the ability to clone these genes. However, the genetic infrastructure required for the positional cloning in zebrafish is still in its infancy. Here we report a reference cross panel of DNA, consisting of 520 F2 progeny (1040 meioses) that has been anchored to a zebrafish genetic linkage map by 102 simple sequence length polymorphisms. This reference cross DNA provides: (1) a panel of DNA from the cross that was used to construct the genetic linkage map, upon which polymorphic gene(s) and genetic markers can be mapped; (2) a fine order mapping tool, with a maximum resolution of 0.1 cM; and (3) a foundation for the development of a physical map (an ordered array of clones each containing a known portion of the genome). This reference cross DNA will serve as a resource enabling investigators to relate genes or genetic markers directly to a single genetic linkage map and avoid the problem of integrating different maps with different genetic markers, as must be currently done when using randomly amplified polymorphic DNA markers, or as has occurred with human genetic linkage maps.",

keywords = "Genetic map, Reference cross, Zebrafish",

author = "Knapik, {Ela W.} and Alec Goodman and {Scott Atkinson}, O. and Roberts, {Carole T.} and Masahide Shiozawa and Sim, {Ch{\"a}ng U.} and Sarah Weksler-Zangen and Trolliet, {Maria R.} and Corey Futrell and Innes, {Brendan A.} and George Koike and McLaughlin, {Michael G.} and Luc Pierre and Simon, {Jason S.} and Eduardo Vilallonga and Millie Roy and Chiang, {Pei Wen} and Fishman, {Mark C.} and Wolfgang Driever and Jacob, {Howard J.}",

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AU - Goodman, Alec

AU - Scott Atkinson, O.

AU - Roberts, Carole T.

AU - Shiozawa, Masahide

AU - Sim, Chäng U.

AU - Weksler-Zangen, Sarah

AU - Trolliet, Maria R.

AU - Futrell, Corey

AU - Innes, Brendan A.

AU - Koike, George

AU - McLaughlin, Michael G.

AU - Pierre, Luc

AU - Simon, Jason S.

AU - Vilallonga, Eduardo

AU - Roy, Millie

AU - Chiang, Pei Wen

AU - Fishman, Mark C.

AU - Driever, Wolfgang

AU - Jacob, Howard J.

PY - 1996

Y1 - 1996

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AB - The ultimate informativeness of the zebrafish mutations described in this issue will rest in part on the ability to clone these genes. However, the genetic infrastructure required for the positional cloning in zebrafish is still in its infancy. Here we report a reference cross panel of DNA, consisting of 520 F2 progeny (1040 meioses) that has been anchored to a zebrafish genetic linkage map by 102 simple sequence length polymorphisms. This reference cross DNA provides: (1) a panel of DNA from the cross that was used to construct the genetic linkage map, upon which polymorphic gene(s) and genetic markers can be mapped; (2) a fine order mapping tool, with a maximum resolution of 0.1 cM; and (3) a foundation for the development of a physical map (an ordered array of clones each containing a known portion of the genome). This reference cross DNA will serve as a resource enabling investigators to relate genes or genetic markers directly to a single genetic linkage map and avoid the problem of integrating different maps with different genetic markers, as must be currently done when using randomly amplified polymorphic DNA markers, or as has occurred with human genetic linkage maps.

KW - Genetic map

KW - Reference cross

KW - Zebrafish

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A reference cross DNA panel for zebrafish (Danio rerio) anchored with simple sequence length polymorphisms

Abstract

Keywords

ASJC Scopus subject areas

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