Abstract
A recent study by Thomas O'Halloran and his group at Northwestern University (Avarez et al. Sciencexpress, www.scienceexpress.org, 26 November 2009) has provided insights into how tetrathiomolybdate inhibits copper-trafficking proteins through metal cluster formation. The broader context of the work provides an attractive explanation of the long recognized but poorly understood antagonistic effects of Mo and Cu in living organisms.
Original language | English (US) |
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Pages (from-to) | 8-9 |
Number of pages | 2 |
Journal | Chemistry and Biology |
Volume | 17 |
Issue number | 1 |
DOIs | |
State | Published - Jan 29 2010 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Pharmacology
- Drug Discovery
- Clinical Biochemistry