A Tale of Two Metals

Ninian J. Blackburn

doi:10.1016/j.chembiol.2010.01.004

A Tale of Two Metals

Ninian J. Blackburn

Chemical Physiology and Biochemistry

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

A recent study by Thomas O'Halloran and his group at Northwestern University (Avarez et al. Sciencexpress, www.scienceexpress.org, 26 November 2009) has provided insights into how tetrathiomolybdate inhibits copper-trafficking proteins through metal cluster formation. The broader context of the work provides an attractive explanation of the long recognized but poorly understood antagonistic effects of Mo and Cu in living organisms.

Original language	English (US)
Pages (from-to)	8-9
Number of pages	2
Journal	Chemistry and Biology
Volume	17
Issue number	1
DOIs	https://doi.org/10.1016/j.chembiol.2010.01.004
State	Published - Jan 29 2010

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmacology
Drug Discovery
Clinical Biochemistry

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10.1016/j.chembiol.2010.01.004

Cite this

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abstract = "A recent study by Thomas O'Halloran and his group at Northwestern University (Avarez et al. Sciencexpress, www.scienceexpress.org, 26 November 2009) has provided insights into how tetrathiomolybdate inhibits copper-trafficking proteins through metal cluster formation. The broader context of the work provides an attractive explanation of the long recognized but poorly understood antagonistic effects of Mo and Cu in living organisms.",

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AB - A recent study by Thomas O'Halloran and his group at Northwestern University (Avarez et al. Sciencexpress, www.scienceexpress.org, 26 November 2009) has provided insights into how tetrathiomolybdate inhibits copper-trafficking proteins through metal cluster formation. The broader context of the work provides an attractive explanation of the long recognized but poorly understood antagonistic effects of Mo and Cu in living organisms.

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A Tale of Two Metals

Abstract

ASJC Scopus subject areas

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