Acute Pancreatitis Due to Hyperchylomicronemia

Research output: Chapter in Book/Report/Conference proceedingChapter


Chylomicronemia-induced pancreatitis is a potentially life-threatening condition that warrants emergency treatment. Most patients with this problem have an underlying genetic disorder of triglyceride metabolism which is superimposed on one or more forms of secondary hypertriglyceridemia, such as uncontrolled diabetes, alcohol intake, and excess dietary fat intake. Eruptive xanthomas, lipemia retinalis, and lipemic plasma are signs of chylomicronemia that may be identified by the clinician. Treatment of chylomicronemia-induced pancreatitis is focused on correction of the chylomicronemia as well as reversal of the factors that may be aggravating hypertriglyceridemia. Long-term therapy requires extensive lifestyle changes, often with the addition of triglyceride-lowering medications. A very low-fat diet, avoidance of alcohol, regular exercise, and sustainable weight loss are important components of the therapeutic intervention. Patients who are compliant with their treatment regimen can often avoid a recurrence of pancreatitis, but recurrent pancreatitis occurs in many patients.

Original languageEnglish (US)
Title of host publicationContemporary Endocrinology
PublisherHumana Press Inc.
Number of pages19
StatePublished - 2021

Publication series

NameContemporary Endocrinology
ISSN (Print)2523-3785
ISSN (Electronic)2523-3793


  • Acute pancreatitis
  • Cystic fibrosis transmembrane regulator
  • Fenofibric acid
  • Plasma triglyceride concentration
  • Triglyceride metabolism

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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