Abstract
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia defined by a balanced translocation between chromosomes 15 and 17 resulting in fusion of the promyelocytic leukemia gene (PML) on chromosome 15 with the retinoic acid receptor-alpha gene (RARα) on chromosome 17. APL often presents with pancytopenia and is associated with a life threatening coagulopathy making prompt diagnosis and initiation of therapy critical. We report an unusual case of APL in a 59 year old female without peripheral blood abnormalities or diffuse marrow involvement. Clinical and radiographic findings were initially interpreted as metastatic osseous disease but ultimately found to be APL.
Original language | English (US) |
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Pages (from-to) | 36-37 |
Number of pages | 2 |
Journal | Leukemia Research Reports |
Volume | 9 |
DOIs | |
State | Published - 2018 |
ASJC Scopus subject areas
- Hematology
- Oncology