Acute reversible lens opacity: Fine structure changes

Calvin Hanna; F. T. Fraunfelder

doi:10.1016/0014-4835(71)90088-1

Acute reversible lens opacity: Fine structure changes

Calvin Hanna
, F. T. Fraunfelder

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Acute reversible lens opacities were produced in anesthetized or postmortem hamsters by taping the eyelids open. Light microscopic observations of the cataractous lenses revealed no change. Only the anterior surface lens cells exhibited electron microscopic alterations, which included a swelling of the cellular and nuclear membranes and a corresponding condensation of cytoplasmic contents. Postmortem lens opacity changes were found only in the epithelial cells, and extensive dilation of the endoplasmic reticulum was observed. These changes are consistent with an acute increase in the ion content in the anterior chamber.

Original language	English (US)
Pages (from-to)	181-182,IN15-IN18,183
Journal	Experimental Eye Research
Volume	12
Issue number	2
DOIs	https://doi.org/10.1016/0014-4835(71)90088-1
State	Published - Sep 1971
Externally published	Yes

Funding

* This inveetigation was supported in part Eye Institute, U.S. Public Health Service.

Funders
National Eye Institute and Casey Eye Institute
U.S. Public Health Service

ASJC Scopus subject areas

Ophthalmology
Sensory Systems
Cellular and Molecular Neuroscience

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10.1016/0014-4835(71)90088-1

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title = "Acute reversible lens opacity: Fine structure changes",

abstract = "Acute reversible lens opacities were produced in anesthetized or postmortem hamsters by taping the eyelids open. Light microscopic observations of the cataractous lenses revealed no change. Only the anterior surface lens cells exhibited electron microscopic alterations, which included a swelling of the cellular and nuclear membranes and a corresponding condensation of cytoplasmic contents. Postmortem lens opacity changes were found only in the epithelial cells, and extensive dilation of the endoplasmic reticulum was observed. These changes are consistent with an acute increase in the ion content in the anterior chamber.",

author = "Calvin Hanna and Fraunfelder, \{F. T.\}",

note = "Funding Information: * This inveetigation was supported in part Eye Institute, U.S. Public Health Service.",

year = "1971",

month = sep,

doi = "10.1016/0014-4835(71)90088-1",

language = "English (US)",

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T1 - Acute reversible lens opacity

T2 - Fine structure changes

AU - Hanna, Calvin

AU - Fraunfelder, F. T.

N1 - Funding Information: * This inveetigation was supported in part Eye Institute, U.S. Public Health Service.

PY - 1971/9

Y1 - 1971/9

N2 - Acute reversible lens opacities were produced in anesthetized or postmortem hamsters by taping the eyelids open. Light microscopic observations of the cataractous lenses revealed no change. Only the anterior surface lens cells exhibited electron microscopic alterations, which included a swelling of the cellular and nuclear membranes and a corresponding condensation of cytoplasmic contents. Postmortem lens opacity changes were found only in the epithelial cells, and extensive dilation of the endoplasmic reticulum was observed. These changes are consistent with an acute increase in the ion content in the anterior chamber.

AB - Acute reversible lens opacities were produced in anesthetized or postmortem hamsters by taping the eyelids open. Light microscopic observations of the cataractous lenses revealed no change. Only the anterior surface lens cells exhibited electron microscopic alterations, which included a swelling of the cellular and nuclear membranes and a corresponding condensation of cytoplasmic contents. Postmortem lens opacity changes were found only in the epithelial cells, and extensive dilation of the endoplasmic reticulum was observed. These changes are consistent with an acute increase in the ion content in the anterior chamber.

UR - https://www.scopus.com/pages/publications/0015119928

UR - https://www.scopus.com/pages/publications/0015119928#tab=citedBy

U2 - 10.1016/0014-4835(71)90088-1

DO - 10.1016/0014-4835(71)90088-1

M3 - Article

C2 - 5119352

AN - SCOPUS:0015119928

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SP - 181-182,IN15-IN18,183

JO - Experimental Eye Research

JF - Experimental Eye Research

IS - 2

ER -

Acute reversible lens opacity: Fine structure changes

Abstract

Funding

ASJC Scopus subject areas

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