TY - JOUR
T1 - Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity
AU - Nguyen, Thanh Tin P.
AU - Ni, Shuibin
AU - Khan, Shanjida
AU - Wei, Xiang
AU - Ostmo, Susan
AU - Chiang, Michael F.
AU - Jia, Yali
AU - Huang, David
AU - Jian, Yifan
AU - Campbell, J. Peter
N1 - Publisher Copyright:
Copyright © 2022 Nguyen, Ni, Khan, Wei, Ostmo, Chiang, Jia, Huang, Jian and Campbell.
PY - 2022/1/18
Y1 - 2022/1/18
N2 - Recent advances in portable optical coherence tomography (OCT) and OCT angiography (OCTA) have resulted in wider fields of view (FOV) and shorter capture times, further expanding the potential clinical role of OCT technology in the diagnosis and management of retinopathy of prematurity (ROP). Using a prototype, handheld OCT device, retinal imaging was obtained in non-sedated infants in the neonatal intensive care unit (NICU) as well as sedated infants in the operating room of Oregon Health & Science University (OHSU) Hospital. In this observational study, we provide an overview of potential advantages of OCT-based disease assessment in ROP. We observed that next-generation OCT imaging (a) may be sufficient for objective diagnosis and zone/stage/plus disease categorization, (b) allows for minimally-invasive longitudinal monitoring of disease progression and post-treatment course, (c) provides three-dimensional mapping of the vitreoretinal interface, and (d) with OCTA, enables dye-free visualization of normal and pathologic vascular development.
AB - Recent advances in portable optical coherence tomography (OCT) and OCT angiography (OCTA) have resulted in wider fields of view (FOV) and shorter capture times, further expanding the potential clinical role of OCT technology in the diagnosis and management of retinopathy of prematurity (ROP). Using a prototype, handheld OCT device, retinal imaging was obtained in non-sedated infants in the neonatal intensive care unit (NICU) as well as sedated infants in the operating room of Oregon Health & Science University (OHSU) Hospital. In this observational study, we provide an overview of potential advantages of OCT-based disease assessment in ROP. We observed that next-generation OCT imaging (a) may be sufficient for objective diagnosis and zone/stage/plus disease categorization, (b) allows for minimally-invasive longitudinal monitoring of disease progression and post-treatment course, (c) provides three-dimensional mapping of the vitreoretinal interface, and (d) with OCTA, enables dye-free visualization of normal and pathologic vascular development.
KW - handheld optical coherence tomography
KW - optical coherence tomography
KW - optical coherence tomography with angiography
KW - pediatric retina
KW - retinopathy of prematurity
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U2 - 10.3389/fped.2021.797684
DO - 10.3389/fped.2021.797684
M3 - Article
AN - SCOPUS:85123929619
SN - 2296-2360
VL - 9
JO - Frontiers in Pediatrics
JF - Frontiers in Pediatrics
M1 - 797684
ER -