Airway responsiveness in atopic dermatitis

Alan F. Barker; Carol A. Hirshman; Ray D'Silva; Jon Hanifin

doi:10.1016/0091-6749(91)90122-5

Airway responsiveness in atopic dermatitis

Alan F. Barker, Carol A. Hirshman, Ray D'Silva, Jon Hanifin

Pulmonary and Critical Care Medicine

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Twelve of 123 patients with atopic dermatitis (AD) were screened by questionnaire and spirometry for the absence of smoking, hay fever, and respiratory disorders. Seven of these 12 patients had a positive methacholine challenge test. None of eight patients with another skin disorder, psoriasis, screened in a similar fashion, had a positive methacholine challenge. We conclude that hyperresponsive airways are a frequent finding in patients with AD and that similar mechanisms may account for the cutaneous physiologic and pharmacologic abnormalities that have been observed in AD.

Original language	English (US)
Pages (from-to)	780-783
Number of pages	4
Journal	The Journal of Allergy and Clinical Immunology
Volume	87
Issue number	4
DOIs	https://doi.org/10.1016/0091-6749(91)90122-5
State	Published - Apr 1991

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1016/0091-6749(91)90122-5

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title = "Airway responsiveness in atopic dermatitis",

abstract = "Twelve of 123 patients with atopic dermatitis (AD) were screened by questionnaire and spirometry for the absence of smoking, hay fever, and respiratory disorders. Seven of these 12 patients had a positive methacholine challenge test. None of eight patients with another skin disorder, psoriasis, screened in a similar fashion, had a positive methacholine challenge. We conclude that hyperresponsive airways are a frequent finding in patients with AD and that similar mechanisms may account for the cutaneous physiologic and pharmacologic abnormalities that have been observed in AD.",

author = "Barker, {Alan F.} and Hirshman, {Carol A.} and Ray D'Silva and Jon Hanifin",

note = "Funding Information: From the Departments of *Internal Medicine, **Anesthesiology. and ***Dermatology, Oregon Health Services University. Port-land, Ore. Supported by Public Health Service Grants AI 15557, AI 18615. HL 25831, and Biomedical Research Support Grant funds. Received for publication Oct. 24. 1989. Revised Nov. 21, 1990. Accepted for publication Nov. 27, 1990. Reprint requests: Alan F. Barker, MD, Pulmonary & Critical Care. 3181 SW Sam Jackson Park Rd., Portland, OR 97201.",

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doi = "10.1016/0091-6749(91)90122-5",

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AU - Barker, Alan F.

AU - Hirshman, Carol A.

AU - D'Silva, Ray

AU - Hanifin, Jon

N1 - Funding Information: From the Departments of *Internal Medicine, **Anesthesiology. and ***Dermatology, Oregon Health Services University. Port-land, Ore. Supported by Public Health Service Grants AI 15557, AI 18615. HL 25831, and Biomedical Research Support Grant funds. Received for publication Oct. 24. 1989. Revised Nov. 21, 1990. Accepted for publication Nov. 27, 1990. Reprint requests: Alan F. Barker, MD, Pulmonary & Critical Care. 3181 SW Sam Jackson Park Rd., Portland, OR 97201.

PY - 1991/4

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N2 - Twelve of 123 patients with atopic dermatitis (AD) were screened by questionnaire and spirometry for the absence of smoking, hay fever, and respiratory disorders. Seven of these 12 patients had a positive methacholine challenge test. None of eight patients with another skin disorder, psoriasis, screened in a similar fashion, had a positive methacholine challenge. We conclude that hyperresponsive airways are a frequent finding in patients with AD and that similar mechanisms may account for the cutaneous physiologic and pharmacologic abnormalities that have been observed in AD.

AB - Twelve of 123 patients with atopic dermatitis (AD) were screened by questionnaire and spirometry for the absence of smoking, hay fever, and respiratory disorders. Seven of these 12 patients had a positive methacholine challenge test. None of eight patients with another skin disorder, psoriasis, screened in a similar fashion, had a positive methacholine challenge. We conclude that hyperresponsive airways are a frequent finding in patients with AD and that similar mechanisms may account for the cutaneous physiologic and pharmacologic abnormalities that have been observed in AD.

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Airway responsiveness in atopic dermatitis

Abstract

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