Amniocentesis results and novel proteomic analysis in a case of occult candidal chorioamnionitis

Julie T. Crawford; Leonardo Pereira; John Buckmaster; Michael G. Gravett; Jorge E. Tolosa

doi:10.1080/14767050600738289

Amniocentesis results and novel proteomic analysis in a case of occult candidal chorioamnionitis

Julie T. Crawford, Leonardo Pereira, John Buckmaster, Michael G. Gravett, Jorge E. Tolosa

Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

We report a case of subclinical Candida albicans chorioamnionitis with mid-trimester cervical dilation diagnosed by amniotic fluid culture and Gram stain. Proteomic analysis of amniotic fluid demonstrated protein biomarkers previously associated only with bacterial intra-amniotic infections. We hypothesize that since amniotic fluid culture of yeast may take days, novel tests such as proteomic profiling may lead to the development of rapid diagnostic tests for fungal intra-amniotic infections.

Original language	English (US)
Pages (from-to)	667-670
Number of pages	4
Journal	Journal of Maternal-Fetal and Neonatal Medicine
Volume	19
Issue number	10
DOIs	https://doi.org/10.1080/14767050600738289
State	Published - Oct 1 2006

Keywords

Amniocentesis
Candidal infection
Chorioamnionitis
Proteomics

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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10.1080/14767050600738289

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abstract = "We report a case of subclinical Candida albicans chorioamnionitis with mid-trimester cervical dilation diagnosed by amniotic fluid culture and Gram stain. Proteomic analysis of amniotic fluid demonstrated protein biomarkers previously associated only with bacterial intra-amniotic infections. We hypothesize that since amniotic fluid culture of yeast may take days, novel tests such as proteomic profiling may lead to the development of rapid diagnostic tests for fungal intra-amniotic infections.",

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AU - Pereira, Leonardo

AU - Buckmaster, John

AU - Gravett, Michael G.

AU - Tolosa, Jorge E.

PY - 2006/10/1

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N2 - We report a case of subclinical Candida albicans chorioamnionitis with mid-trimester cervical dilation diagnosed by amniotic fluid culture and Gram stain. Proteomic analysis of amniotic fluid demonstrated protein biomarkers previously associated only with bacterial intra-amniotic infections. We hypothesize that since amniotic fluid culture of yeast may take days, novel tests such as proteomic profiling may lead to the development of rapid diagnostic tests for fungal intra-amniotic infections.

AB - We report a case of subclinical Candida albicans chorioamnionitis with mid-trimester cervical dilation diagnosed by amniotic fluid culture and Gram stain. Proteomic analysis of amniotic fluid demonstrated protein biomarkers previously associated only with bacterial intra-amniotic infections. We hypothesize that since amniotic fluid culture of yeast may take days, novel tests such as proteomic profiling may lead to the development of rapid diagnostic tests for fungal intra-amniotic infections.

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KW - Candidal infection

KW - Chorioamnionitis

KW - Proteomics

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Amniocentesis results and novel proteomic analysis in a case of occult candidal chorioamnionitis

Abstract

Keywords

ASJC Scopus subject areas

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