An IRKO in the Podo: Impaired insulin signaling in podocytes and the pathogenesis of diabetic nephropathy

Susan B. Gurley; Thomas M. Coffman

doi:10.1016/j.cmet.2010.09.007

An IRKO in the Podo: Impaired insulin signaling in podocytes and the pathogenesis of diabetic nephropathy

Susan B. Gurley, Thomas M. Coffman

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

Despite its high prevalence, the mechanisms causing diabetic kidney disease remain poorly understood. In this issue of Cell Metabolism, Welsh et al. (2010) show that elimination of insulin receptors from the glomerular podocyte, a cell that is central to the pathogenesis of proteinuric renal diseases, recapitulates many features of human diabetic nephropathy.

Original language	English (US)
Pages (from-to)	311-312
Number of pages	2
Journal	Cell Metabolism
Volume	12
Issue number	4
DOIs	https://doi.org/10.1016/j.cmet.2010.09.007
State	Published - Oct 6 2010
Externally published	Yes

ASJC Scopus subject areas

Physiology
Molecular Biology
Cell Biology

Access to Document

10.1016/j.cmet.2010.09.007

Cite this

@article{b4b2df270fd64ac3b2267ffe4f6a5d27,

title = "An IRKO in the Podo: Impaired insulin signaling in podocytes and the pathogenesis of diabetic nephropathy",

abstract = "Despite its high prevalence, the mechanisms causing diabetic kidney disease remain poorly understood. In this issue of Cell Metabolism, Welsh et al. (2010) show that elimination of insulin receptors from the glomerular podocyte, a cell that is central to the pathogenesis of proteinuric renal diseases, recapitulates many features of human diabetic nephropathy.",

author = "Gurley, {Susan B.} and Coffman, {Thomas M.}",

year = "2010",

month = oct,

day = "6",

doi = "10.1016/j.cmet.2010.09.007",

language = "English (US)",

volume = "12",

pages = "311--312",

journal = "Cell Metabolism",

issn = "1550-4131",

publisher = "Cell Press",

number = "4",

}

TY - JOUR

T1 - An IRKO in the Podo

T2 - Impaired insulin signaling in podocytes and the pathogenesis of diabetic nephropathy

AU - Gurley, Susan B.

AU - Coffman, Thomas M.

PY - 2010/10/6

Y1 - 2010/10/6

N2 - Despite its high prevalence, the mechanisms causing diabetic kidney disease remain poorly understood. In this issue of Cell Metabolism, Welsh et al. (2010) show that elimination of insulin receptors from the glomerular podocyte, a cell that is central to the pathogenesis of proteinuric renal diseases, recapitulates many features of human diabetic nephropathy.

AB - Despite its high prevalence, the mechanisms causing diabetic kidney disease remain poorly understood. In this issue of Cell Metabolism, Welsh et al. (2010) show that elimination of insulin receptors from the glomerular podocyte, a cell that is central to the pathogenesis of proteinuric renal diseases, recapitulates many features of human diabetic nephropathy.

UR - http://www.scopus.com/inward/record.url?scp=77957664865&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77957664865&partnerID=8YFLogxK

U2 - 10.1016/j.cmet.2010.09.007

DO - 10.1016/j.cmet.2010.09.007

M3 - Short survey

C2 - 20889121

AN - SCOPUS:77957664865

SN - 1550-4131

VL - 12

SP - 311

EP - 312

JO - Cell Metabolism

JF - Cell Metabolism

IS - 4

ER -

An IRKO in the Podo: Impaired insulin signaling in podocytes and the pathogenesis of diabetic nephropathy

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this