Anaesthetic management of patients with bronchospastic disease

H. G.G. Kingston, C. A. Hirshman

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


This article presents a brief resume of airway anatomy, physiology and pharmacology, a disccussion of mechanisms underlying airway hyper-reactivity, preoperative assessment of the patient with bronchospasm and a critical evaluation of effects of anaesthetics in reactive airway disease. The airway of the patient with bronchospastic disease is a dynamic structure. Changes in airway calibre profoundly effect the distribution of gases within the lung. Therefore, the anaesthesiologist must attempt to prevent or reverse the occurrence of airway constriction. This may be accomplished by blocking parasympathetic irritant reflexes, by directly relaxing airway smooth muscle, by inhibiting mediator release and by augmenting β2-adrenergic sympathetic activity.

Original languageEnglish (US)
Pages (from-to)377-396
Number of pages20
JournalClinics in Anaesthesiology
Issue number2
StatePublished - 1983
Externally publishedYes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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