Anal cancer: Current standards in care and recent changes in practice

Ravi Shridhar; David Shibata; Emily Chan; Charles R. Thomas

doi:10.3322/caac.21259

Anal cancer: Current standards in care and recent changes in practice

Ravi Shridhar, David Shibata, Emily Chan, Charles R. Thomas

Research output: Contribution to journal › Review article › peer-review

74 Scopus citations

Abstract

Answer questions and earn CME/CNE The management of squamous cell carcinomas of the anal canal has evolved from surgery as first-line treatment to curative chemoradiation, with surgery reserved for salvage. Significant progress has been made in understanding how to most effectively deliver chemotherapy and reduce toxicity through advancements in radiation delivery. The purpose of this article is to review the multimodality approach to the diagnosis and management of anal cancer based on a review of the published data and in light of available guidelines. CA Cancer J Clin 2015;65: 139-162.

Original language	English (US)
Pages (from-to)	139-162
Number of pages	24
Journal	CA Cancer Journal for Clinicians
Volume	65
Issue number	2
DOIs	https://doi.org/10.3322/caac.21259
State	Published - Mar 1 2015
Externally published	Yes

Keywords

abdominoperineal resection
anal cancer
brachytherapy
chemoradiation
chemotherapy
intensity modulated radiation therapy
quality of life
salvage therapy
sentinel lymph node biopsy
squamous cell carcinoma

ASJC Scopus subject areas

Hematology
Oncology

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10.3322/caac.21259

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title = "Anal cancer: Current standards in care and recent changes in practice",

abstract = "Answer questions and earn CME/CNE The management of squamous cell carcinomas of the anal canal has evolved from surgery as first-line treatment to curative chemoradiation, with surgery reserved for salvage. Significant progress has been made in understanding how to most effectively deliver chemotherapy and reduce toxicity through advancements in radiation delivery. The purpose of this article is to review the multimodality approach to the diagnosis and management of anal cancer based on a review of the published data and in light of available guidelines. CA Cancer J Clin 2015;65: 139-162.",

keywords = "abdominoperineal resection, anal cancer, brachytherapy, chemoradiation, chemotherapy, intensity modulated radiation therapy, quality of life, salvage therapy, sentinel lymph node biopsy, squamous cell carcinoma",

author = "Ravi Shridhar and David Shibata and Emily Chan and Thomas, {Charles R.}",

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AU - Thomas, Charles R.

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AB - Answer questions and earn CME/CNE The management of squamous cell carcinomas of the anal canal has evolved from surgery as first-line treatment to curative chemoradiation, with surgery reserved for salvage. Significant progress has been made in understanding how to most effectively deliver chemotherapy and reduce toxicity through advancements in radiation delivery. The purpose of this article is to review the multimodality approach to the diagnosis and management of anal cancer based on a review of the published data and in light of available guidelines. CA Cancer J Clin 2015;65: 139-162.

KW - abdominoperineal resection

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Anal cancer: Current standards in care and recent changes in practice

Abstract

Keywords

ASJC Scopus subject areas

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