Antisera to an axolemma-enriched fraction inhibit neurite outgrowth and destroy axons in vitro

Dennis N. Bourdette; Fredrick J. Seil; John W. Bigbee; George H. DeVries; Margaret M. Garwood; Harish C. Agrawal

doi:10.1016/0006-8993(86)91313-2

Antisera to an axolemma-enriched fraction inhibit neurite outgrowth and destroy axons in vitro

Dennis N. Bourdette, Fredrick J. Seil, John W. Bigbee, George H. DeVries, Margaret M. Garwood, Harish C. Agrawal

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Antisera prepared to an axolemma-enriched fraction derived from rat brain inhibited neurite outgrowth and destroyed mature axons in spinal cord-dorsal root ganglia cultures. Similar antibody-mediated anti-axon effects may be important in some diseases of the human nervous system.

Original language	English (US)
Pages (from-to)	333-337
Number of pages	5
Journal	Brain research
Volume	366
Issue number	1-2
DOIs	https://doi.org/10.1016/0006-8993(86)91313-2
State	Published - Feb 26 1986
Externally published	Yes

Keywords

anti-axolemma antibody
anti-axon antibody
axolemma
neural tissue culture

ASJC Scopus subject areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(86)91313-2

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title = "Antisera to an axolemma-enriched fraction inhibit neurite outgrowth and destroy axons in vitro",

abstract = "Antisera prepared to an axolemma-enriched fraction derived from rat brain inhibited neurite outgrowth and destroyed mature axons in spinal cord-dorsal root ganglia cultures. Similar antibody-mediated anti-axon effects may be important in some diseases of the human nervous system.",

keywords = "anti-axolemma antibody, anti-axon antibody, axolemma, neural tissue culture",

author = "Bourdette, {Dennis N.} and Seil, {Fredrick J.} and Bigbee, {John W.} and DeVries, {George H.} and Garwood, {Margaret M.} and Agrawal, {Harish C.}",

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T1 - Antisera to an axolemma-enriched fraction inhibit neurite outgrowth and destroy axons in vitro

AU - Bourdette, Dennis N.

AU - Seil, Fredrick J.

AU - Bigbee, John W.

AU - DeVries, George H.

AU - Garwood, Margaret M.

AU - Agrawal, Harish C.

PY - 1986/2/26

Y1 - 1986/2/26

N2 - Antisera prepared to an axolemma-enriched fraction derived from rat brain inhibited neurite outgrowth and destroyed mature axons in spinal cord-dorsal root ganglia cultures. Similar antibody-mediated anti-axon effects may be important in some diseases of the human nervous system.

AB - Antisera prepared to an axolemma-enriched fraction derived from rat brain inhibited neurite outgrowth and destroyed mature axons in spinal cord-dorsal root ganglia cultures. Similar antibody-mediated anti-axon effects may be important in some diseases of the human nervous system.

KW - anti-axolemma antibody

KW - anti-axon antibody

KW - axolemma

KW - neural tissue culture

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ER -

Antisera to an axolemma-enriched fraction inhibit neurite outgrowth and destroy axons in vitro

Abstract

Keywords

ASJC Scopus subject areas

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