Aortoiliac disease: Two‐dimensional inflow MR angiography with lipid suppression

Susan A. Mulligan, Mark Doyle, Tetsuya Matsuda, D. Bradley Koslin, Philip J. Kenney, Robert E. Barton, Gerald M. Pohost

Research output: Contribution to journalArticlepeer-review


A magnetic resonance (MR) imaging strategy, SLIP (spatially separated lipid presaturation), which can be incorporated into existing MR imaging and MR angiographic techniques, has been developed to suppress lipid signal. The authors report the clinical application of this technique, with a triple comparison of two‐dimensional inflow MR angiography, with and without SLIP, and x‐ray angiography in patients with aortoiliac disease. SLIP improved visualization of arterial segments, with 50 of 63 (79%) arterial segments visualized versus 41 of 63 (65%) for non‐SLIP MR angiography. The SLIP strategy aids in the depiction of slow or turbulent flow, because the lipid signal is suppressed while the intravascular signal is left undisturbed. Image quality improves because of the combination of decreased background lipid signal intensity and use of the maximum‐intensity‐projection algorithm. Compared with x‐ray arteriography, non‐SLIP MR angiography had a sensitivity and specificity of 60% and 56%, respectively, for detection of lesions with 50%–100% diameter reduction, while SLIP MR angiography had a sensitivity and specificity, respectively, of 53% and 67%.

Original languageEnglish (US)
Pages (from-to)829-834
Number of pages6
JournalJournal of Magnetic Resonance Imaging
Issue number6
StatePublished - Jan 1 1993


  • Arteries, MR. 98.12942,98.129415
  • Arteries, iliac. 98.12942, 98.129415
  • Arteries, stenosis or obstruction, 98.721
  • Comparative studies
  • Pulse sequences
  • Tissue suppression
  • Vascular studies

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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