Applied physiology of glucose control

Kathryn Beardsall, Kevin Yuen, Rachel Williams, David Dunger

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

There is a dynamic equilibrium that maintains a constant and controlled supply of glucose to the tissues, whilst maintaining blood glucose in a narrow range, in both the fed and fasting state. This balance is primarily dependent on the hormonal control of glucose uptake by insulin into the muscles in the fed state, and by glucagon and counter-regulatory hormones leading to glucose release from the liver in the fasted state. If a child presents with abnormal blood glucose control, an understanding of the basic physiology of glucose metabolism can be a valuable guide for both diagnosis and further management.

Original languageEnglish (US)
Pages (from-to)543-548
Number of pages6
JournalCurrent Paediatrics
Volume13
Issue number7
DOIs
StatePublished - Dec 2003

Keywords

  • Diabetes
  • Glucose control
  • Hyperglycaemia
  • Hypoglycaemia
  • Physiology

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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