Abstract
In the presence of an epicardial coronary stenosis, changes in microvascular hemodynamics after the administration of pharmacologic stress agents result in a decrease in myocardial blood volume (MBV) from capillary derecruitment. Because capillaries provide the greatest resistance to flow during maximal hyperemias, changes in capillary volume are closely coupled to changes in hyperemic myocardial blood flow (MBF). A wide array of imaging techniques are now available with myocardial contrast echocardiography to assess both the spatial and temporal aspects of myocardial perfusion, providing many options for the detection of coronary stenosis by evaluating changes in MBV, MBF, or both.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 48-58 |
| Number of pages | 11 |
| Journal | American Journal of Cardiology |
| Volume | 90 |
| Issue number | 10 SUPPL. 1 |
| DOIs | |
| State | Published - Nov 18 2002 |
| Externally published | Yes |
Funding
This work was supported in part by a Mentored Clinical Scientist Development Award No. K08-HL03909 from the National Institutes of Health.
| Funders | Funder number |
|---|---|
| Author National Institutes of Health National Institutes of Health National Institutes of Health National Institutes of Health The Bev Hartig Huntington's Disease Foundation National Institutes of Health | |
| National Institute of Health National Heart, Lung, and Blood Institute | K08HL003909 |
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
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