TY - JOUR
T1 - Aqueous shift reagents for high-resolution cationic nuclear magnetic resonance. III. Dy(TTHA)3-, Tm(TTHA)3-, and Tm(PPP)27-
AU - Chu, Simon C.
AU - Pike, Martin M.
AU - Fossel, Eric T.
AU - Smith, Thomas W.
AU - Balschi, James A.
AU - Springer, Charles S.
N1 - Funding Information:
We thank Dr. Jean Delayre and Mr. Jeffrey Shook for invaluable technical assistance, and Ms. Jean Petrilli and Ms. Pat Gunning for preparation of the typescript. We also thank Dr. Joanne Ingwall for many stimulating discussions and Dr. Valeri Kapelko, and Dr. David Yarmush, and Ms. Nava Shochet for their unpublished results. This work was supported by NSF Grants PCM 8104630 and PCM 8003739 to CSS, NIH Grant HL-28432 to ETF, and NIH Grant HL-18003 to TWS. This work was completed during the tenure of ETF as an Established Investigator of the American Heart Association.
PY - 1984/1
Y1 - 1984/1
N2 - The isotropic hyperfine shifts induced in the 23Na+ resonance by the shift reagents Dy(DPA)33-, Dy(NTA)23-, Dy(PPP)27-, Tm(PPP)27-, Dy(TTHA)3-, and Tm(TTHA)3- are compared under similar conditions. The last three are introduced as shift reagents in this study. The Dy(PPP)37- and Tm(PPP)27- ions cause the largest shifts. However, these shifts are very pH dependent and are readily decreased by the presence of Ca2+ or Mg2+ ions. The Dy(TTHA)3- and Tm(TTHA)3- ions produce quite large shifts which are independent of pH (between 5.5 and 12) and less sensitive to Ca2+ and Mg2+. For a given chelate ligand, the analogous Dy(III) and Tm(III) complexes cause hyperfine shifts in opposite directions. However, while the Dy(PPP)27- ion induces an upfield shift, the Dy(TTHA)3- ion induces a downfield shift. Some data on shifts of the 25Mg2+, 39K+, and 87Rb+ resonances are also presented. In addition the 14N peak of NH4+ can be quite effectively shifted.
AB - The isotropic hyperfine shifts induced in the 23Na+ resonance by the shift reagents Dy(DPA)33-, Dy(NTA)23-, Dy(PPP)27-, Tm(PPP)27-, Dy(TTHA)3-, and Tm(TTHA)3- are compared under similar conditions. The last three are introduced as shift reagents in this study. The Dy(PPP)37- and Tm(PPP)27- ions cause the largest shifts. However, these shifts are very pH dependent and are readily decreased by the presence of Ca2+ or Mg2+ ions. The Dy(TTHA)3- and Tm(TTHA)3- ions produce quite large shifts which are independent of pH (between 5.5 and 12) and less sensitive to Ca2+ and Mg2+. For a given chelate ligand, the analogous Dy(III) and Tm(III) complexes cause hyperfine shifts in opposite directions. However, while the Dy(PPP)27- ion induces an upfield shift, the Dy(TTHA)3- ion induces a downfield shift. Some data on shifts of the 25Mg2+, 39K+, and 87Rb+ resonances are also presented. In addition the 14N peak of NH4+ can be quite effectively shifted.
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U2 - 10.1016/0022-2364(84)90189-6
DO - 10.1016/0022-2364(84)90189-6
M3 - Article
AN - SCOPUS:0002424208
SN - 0022-2364
VL - 56
SP - 33
EP - 47
JO - Journal of Magnetic Resonance (1969)
JF - Journal of Magnetic Resonance (1969)
IS - 1
ER -