Athletic Shoe Dermatitis Contact Allergy to Ethyl Butyl Thiourea

Janet L. Roberts, Jon M. Hanifin

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Ten patients with severe foot dermatitis were found to be highly allergic to innersole material prepared by Spenco Medical Corporation and used in Nike athletic shoes. Contact allergy testing showed sensitivity to ethyl butyl thiourea, a chemical accelerator in some neoprene (polychloroprene) rubber products. The dermatitis was recalcitrant and in many cases persisted long after discontinuance of wearing Nike shoes, raising the concern that traces of ethyl butyl thiourea or cross-reacting chemicals may be present in other footwear.

Original languageEnglish (US)
Pages (from-to)275-276
Number of pages2
JournalJAMA: The Journal of the American Medical Association
Issue number3
StatePublished - Jan 19 1979

ASJC Scopus subject areas

  • Medicine(all)


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