Attention deficit hyperactivity disorder

Marguerite Matthews, Joel T. Nigg, Damien Fair

Research output: Contribution to journalArticlepeer-review

87 Scopus citations


Over the last two decades, there have been numerous technical and methodological advances available to clinicians and researchers to better understand attention deficit hyperactivity disorder (ADHD) and its etiology. Despite the growing body of literature investigating the disorder’s pathophysiology, ADHD remains a complex psychiatric disorder to characterize. This chapter will briefly review the literature on ADHD, with a focus on its history, the current genetic insights, neurophysiologic theories, and the use of neuroimaging to further understand the etiology. We address some of the major concerns that remain unclear about ADHD, including subtype instability, heterogeneity, and the underlying neural correlates that define the disorder. We highlight that the field of ADHD is rapidly evolving; the descriptions provided here will hopefully provide a sturdy foundation for which to build and improve our understanding of the disorder.

Original languageEnglish (US)
Pages (from-to)235-266
Number of pages32
JournalCurrent topics in behavioral neurosciences
StatePublished - Nov 10 2013


  • Attention
  • Attention deficit hyperactivity disorder
  • Brain development
  • FMRI
  • Functional connectivity
  • Heritability
  • Heterogeneity
  • Hyperactivity
  • Impulsivity
  • Neuropsychiatric disorders
  • Reward system
  •  Executive function

ASJC Scopus subject areas

  • Behavioral Neuroscience


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