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Atypia of undetermined significance in the Milan System for Reporting Salivary Gland Cytopathology: Cystic versus non-cystic masses

Research output: Contribution to journalArticlepeer-review

Abstract

The term “Atypia” has been employed to describe a wide spectrum of cytomorphologic features associated with reactive/inflammatory processes as well as those suspicious for neoplasms in cytology. Similar to other cytopathology reporting systems, the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) has reserved the atypical category for cytology specimens lacking quantitative and/or qualitative cytomorphologic features to be diagnosed with confidence as either non-neoplastic or neoplastic. In MSRSGC, the atypical category is associated with a risk of malignancy and recommendation for clinical management. In this review, we discuss the value of atypical diagnostic category of MSRSGC in both cystic and non-cystic salivary gland lesions by evaluating our institutional case cohort.

Original languageEnglish (US)
Pages (from-to)154-161
Number of pages8
JournalDiagnostic Cytopathology
Volume50
Issue number4
DOIs
StatePublished - Apr 2022
Externally publishedYes

Keywords

  • atypia of undetermined significance
  • cystic versus non-cystic
  • fine needle aspiration
  • Milan system for reporting salivary gland cytopathology
  • salivary gland cytology

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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