TY - JOUR
T1 - Automated Detection of Real-World Falls
T2 - Modeled from People with Multiple Sclerosis
AU - Mosquera-Lopez, Clara
AU - Wan, Eric
AU - Shastry, Mahesh
AU - Folsom, Jonathon
AU - Leitschuh, Joseph
AU - Condon, John
AU - Rajhbeharrysingh, Uma
AU - Hildebrand, Andrea
AU - Cameron, Michelle
AU - Jacobs, Peter G.
N1 - Funding Information:
Manuscript received March 21, 2020; revised October 13, 2020; accepted November 17, 2020. Date of publication November 27, 2020; date of current version June 4, 2021. This work was supported by the Department of Veterans Affairs, Rehabilitation Research and Development Service (Award RX001831-01A1). Peter G. Jacobs and Eric Wan have a financial interest in MotioSens, a company that may have a commercial interest in the results of this research and technology. (Corresponding author: Clara Mosquera-Lopez.) Clara Mosquera-Lopez, Mahesh Shastry, Jonathon Folsom, Joseph Leitschuh, Uma Rajhbeharrysingh, and Peter G. Jacobs are with the Department of Biomedical Engineering, Oregon Health & Science University, Portland 97239, OR USA (e-mail: mosquera@ohsu.edu; mahesh.shastry@gmail.com; folsomj@ohsu.edu; leitschj@ohsu.edu; rsingh.uma@gmail.com; jacobsp@ohsu.edu).
Publisher Copyright:
© 2013 IEEE.
PY - 2021/6
Y1 - 2021/6
N2 - Falls are a major health problem with one in three people over the age of 65 falling each year, oftentimes causing hip fractures, disability, reduced mobility, hospitalization and death. A major limitation in fall detection algorithm development is an absence of real-world falls data. Fall detection algorithms are typically trained on simulated fall data that contain a well-balanced number of examples of falls and activities of daily living. However, real-world falls occur infrequently, making them difficult to capture and causing severe data imbalance. People with multiple sclerosis (MS) fall frequently, and their risk of falling increases with disease progression. Because of their high fall incidence, people with MS provide an ideal model for studying falls. This paper describes the development of a context-aware fall detection system based on inertial sensors and time of flight sensors that is robust to imbalance, which is trained and evaluated on real-world falls in people with MS. The algorithm uses an auto-encoder that detects fall candidates using reconstruction error of accelerometer signals followed by a hyper-ensemble of balanced random forests trained using both acceleration and movement features. On a clinical dataset obtained from 25 people with MS monitored over eight weeks during free-living conditions, 54 falls were observed and our system achieved a sensitivity of 92.14%, and false-positive rate of 0.65 false alarms per day.
AB - Falls are a major health problem with one in three people over the age of 65 falling each year, oftentimes causing hip fractures, disability, reduced mobility, hospitalization and death. A major limitation in fall detection algorithm development is an absence of real-world falls data. Fall detection algorithms are typically trained on simulated fall data that contain a well-balanced number of examples of falls and activities of daily living. However, real-world falls occur infrequently, making them difficult to capture and causing severe data imbalance. People with multiple sclerosis (MS) fall frequently, and their risk of falling increases with disease progression. Because of their high fall incidence, people with MS provide an ideal model for studying falls. This paper describes the development of a context-aware fall detection system based on inertial sensors and time of flight sensors that is robust to imbalance, which is trained and evaluated on real-world falls in people with MS. The algorithm uses an auto-encoder that detects fall candidates using reconstruction error of accelerometer signals followed by a hyper-ensemble of balanced random forests trained using both acceleration and movement features. On a clinical dataset obtained from 25 people with MS monitored over eight weeks during free-living conditions, 54 falls were observed and our system achieved a sensitivity of 92.14%, and false-positive rate of 0.65 false alarms per day.
KW - Automated fall detection
KW - auto-encoder
KW - imbalance-aware classification
KW - multiple sclerosis
KW - random forest hyper-ensemble
KW - real-world falls
UR - http://www.scopus.com/inward/record.url?scp=85097423548&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85097423548&partnerID=8YFLogxK
U2 - 10.1109/JBHI.2020.3041035
DO - 10.1109/JBHI.2020.3041035
M3 - Article
C2 - 33245698
AN - SCOPUS:85097423548
SN - 2168-2194
VL - 25
SP - 1975
EP - 1984
JO - IEEE journal of biomedical and health informatics
JF - IEEE journal of biomedical and health informatics
IS - 6
M1 - 9272845
ER -