Benign angioedema after thrombolysis for acute stroke

Nikolaos I.H. Papamitsakis, Jennifer Kuyl, Helmi L. Lutsep, Wayne M. Clark

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


We present a case of acute angioedema after administration of recombinant tissue plasminogen activator (t-PA) for acute ischemic stroke. Our patient was treated with t-PA in accordance with the National Institute of Neurological Disorders and Stroke (NINDS) protocol, and subsequently developed angioedema of the lower lip that subsided within 2 hours. Five patients who required upper airway control after the use of t-PA for ischemic stroke have been reported in the literature. Although the outcome in our case was excellent, development of angioedema after t-PA administration is a potential complication of which treating physicians need to be aware.

Original languageEnglish (US)
Pages (from-to)79-81
Number of pages3
JournalJournal of Stroke and Cerebrovascular Diseases
Issue number2
StatePublished - 2000


  • Angioedema
  • Stroke
  • T-PA

ASJC Scopus subject areas

  • Surgery
  • Rehabilitation
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine


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