Abstract
Spin-lattice relaxation in the rotating frame magnetic resonance imaging allows for the quantitative assessment of spin-lock contrast within tissues. We describe the utility of spin-lattice relaxation in the rotating frame metrics in characterizing glioblastoma biological heterogeneity. A 84-year-old man presented to our institution with a right frontal temporal mass. Prior tissue sampling from a peripheral nonenhancing lesion was nondiagnostic. Stereotactic image-guided tissue sampling of the nonenhancing T2-fluid-attenuated inversion recovery hyperintense region involving the anterior cingulate gyrus with elevated spin-lattice relaxation in the rotating frame metrics provided a pathologic diagnosis of glioblastoma. This case illustrates the utility of spin-lattice relaxation in the rotating frame magnetic resonance imaging in identifying biologically aggressive regions within glioblastoma.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 827-832 |
| Number of pages | 6 |
| Journal | Radiology Case Reports |
| Volume | 12 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 1 2017 |
Funding
Acknowledgments: This work was funded by grant number 5T32EB001631-07 from the National Institutes of Health Roadmap for Medical Research. The first author thanks Bethany Barajas for her helpful comments regarding this manuscript.
Keywords
- Glioblastoma
- Glioma
- Image-guided
- Spin-lock contrast
- T1rho MRI
- T1ρ MRI
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
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