Brain-Dependent ACTH Secretion from Multiple Heterotopic Pituitaries

John W. Kendall, Catherine Allen

Research output: Contribution to journalArticlepeer-review


Hypophysectomized rats with multiple heterotopic pituitaries have nearly normal adrenal weight and significant, though subnormal, corticosterone secretion. Removal of the entire forebrain, but not decortication, in these animals reduced corticosterone secretion nearly to values found in hypophysectomized control animals. These results indicate that heterotopic pituitary ACTH secretion is dependent on some subcortical portion of the forebrain.

Original languageEnglish (US)
Pages (from-to)335-337
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Issue number2
StatePublished - Jun 1966
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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