TY - JOUR
T1 - Call to action to prevent venous thromboembolism
AU - Wakefield, Thomas W.
AU - McLafferty, Robert B.
AU - Lohr, Joann M.
AU - Caprini, Joseph A.
AU - Gillespie, David L.
AU - Passman, Marc A.
N1 - Funding Information:
The Surgeon General's Call to Action to Prevent Deep Vein Thrombosis and Pulmonary Embolism grew out of a Workshop on DVT/PE held in May 2006 at the National Institute of Health in Bethesda, Maryland. At that time, over 40 experts on behalf of themselves and their organizations presented findings regarding the prevention, diagnosis and treatment of VTE. The workshop was co-chaired by Thomas L. Ortel, MD, PhD, Duke University Medical Center and Samuel Z. Goldhaber, MD, Harvard Medical School. The workshop was hosted by former Surgeon General, Vice Admiral Richard H. Carmona, MD, MPH, FACS; the Deputy Surgeon General and Workshop Chair RADM Kenneth P. Moritsugu, MD, MPH; and the Director of National Heart, Lung and Blood Institute Elizabeth G. Nabel, MD. Members of the American Venous Forum were well represented at this workshop, including Joseph A. Caprini, MD, Robert B. McLafferty, MD, and Thomas W. Wakefield, MD. The workshop highlighted the tremendous gap in understanding and knowledge that exists regarding these thrombotic disorders despite the advances in the prevention, diagnosis, and treatment for these disorders that have been made. Conclusions from that workshop included the need to disseminate information more widely about the availability of effective interventions to prevent and treat DVT/PE, the need to invest in basic scientific, clinical, and epidemiological research related to DVT/PE, and the need to encourage translational research to allow for the latest information to be put into practice. The Surgeon General's Call to Action was proposed by Dr. Carmona at the conclusion of the workshop to provide a mechanism for the development of a coordinated plan to address these issues as listed above. This Call to Action occurred September 15, 2008 and was delivered by Acting Surgeon General, Rear Admiral Steven K. Galson, MD, MPH ( Fig 1 , A), and Elizabeth G. Nabel, MD, Director National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH; Fig 1 , B). Again, the American Venous Forum was well represented with members present Joann M. Lohr MD, Joseph A. Caprini, MD, Marc A. Passman, MD, David L. Gillespie, MD, Robert B. McLafferty, MD, and Thomas W. Wakefield, MD ( Fig 2 ). Additionally, to aid attendees in the work of education in venous disease, the American Venous Forum had a National Venous Screening Program booth setup on site ( Fig 3 ). As Dr. Nabel stated, “It is NHLBI's hope that this Call to Action will stimulate innovative research by investigators who are committed to finding new ways to prevent and treat these conditions…It is critical that we identify new areas of research related to venous biology, DVT/PE, their complications, and clinical interventions. This kind of basic and clinical science is needed to provide a foundation for the development of evidence-based guidelines.” In fact, the NIH has just funded eight new research projects in an RFA entitled “Deep Vein Thrombosis and Venous Disease (R01).” Topics funded are wide ranging and encompass many areas of new research. They include aspects of malignancy and venous thrombosis including the role of tissue factor, procoagulant microparticles and other basic mechanisms of thrombosis in cancer-associated venous thrombosis, new treatment paradigms for childhood venous thrombosis, and new therapeutic targets for venous thrombosis prophylaxis and treatment. Additionally, studies of recurrent venous thrombosis, chronic thrombotic venous disease, and new imaging biomarkers for the prognosis of pulmonary embolism are included.
PY - 2009/6
Y1 - 2009/6
N2 - Deep venous thrombosis and pulmonary embolism, together called venous thromboembolism, remain a serious national health problem. Estimates suggest that over 900,000 cases occur in the United States per year, with 300,000 deaths per year. Because of the significant and serious nature of this problem, a workshop was held in May of 2006, which resulted in the Acting U.S. Public Health Service Surgeon General's Call to Action to Prevent Deep Vein Thrombosis and Pulmonary Embolism. On September 15, 2008, Acting Surgeon General, Rear Admiral Steven K. Galson, MD, MPH, and Elizabeth Nabel, MD, Director National Heart, Lung, and Blood Institute, announced the Call to Action. The Call to Action highlights public awareness about the risk factors, triggering events, and symptoms of venous thrombosis and pulmonary embolism, and encourages the development of evidence based practices for screening, prevention, diagnosis, and treatment of venous thrombosis and pulmonary embolism. It is designed to encourage new scientific investigation in an effort to obtain needed evidence to fill in the gaps of knowledge about venous thrombosis and pulmonary embolism. This knowledge should be quickly and easily disseminated to the public and put into practice by health professionals. The Surgeon General's Call to Action represents one of the most important advances in the field of venous thromboembolism and sets the stage for multidisciplinary efforts to combat this serious national health problem.
AB - Deep venous thrombosis and pulmonary embolism, together called venous thromboembolism, remain a serious national health problem. Estimates suggest that over 900,000 cases occur in the United States per year, with 300,000 deaths per year. Because of the significant and serious nature of this problem, a workshop was held in May of 2006, which resulted in the Acting U.S. Public Health Service Surgeon General's Call to Action to Prevent Deep Vein Thrombosis and Pulmonary Embolism. On September 15, 2008, Acting Surgeon General, Rear Admiral Steven K. Galson, MD, MPH, and Elizabeth Nabel, MD, Director National Heart, Lung, and Blood Institute, announced the Call to Action. The Call to Action highlights public awareness about the risk factors, triggering events, and symptoms of venous thrombosis and pulmonary embolism, and encourages the development of evidence based practices for screening, prevention, diagnosis, and treatment of venous thrombosis and pulmonary embolism. It is designed to encourage new scientific investigation in an effort to obtain needed evidence to fill in the gaps of knowledge about venous thrombosis and pulmonary embolism. This knowledge should be quickly and easily disseminated to the public and put into practice by health professionals. The Surgeon General's Call to Action represents one of the most important advances in the field of venous thromboembolism and sets the stage for multidisciplinary efforts to combat this serious national health problem.
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U2 - 10.1016/j.jvs.2009.01.058
DO - 10.1016/j.jvs.2009.01.058
M3 - Article
C2 - 19497526
AN - SCOPUS:66149141862
SN - 0741-5214
VL - 49
SP - 1620
EP - 1623
JO - Journal of Vascular Surgery
JF - Journal of Vascular Surgery
IS - 6
ER -