Campylobacter jejuni-associated hemolytic-uremic syndrome in a mother and daughter

B. N. Chamovitz, A. I. Hartstein, S. R. Alexander, A. B. Terry, P. Short, R. Katon

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


A mother and daughter with Campylobacter jejuni-associated hemolytic-uremic syndrome (HUS) are discussed. The mother was hospitalized with bloody diarrhea and HUS; C jejuni was isolated from her stool. The 2-year-old daughter had been admitted five days prior to her mother with HUS following a three-day prodrome of vomiting and diarrhea. Multiple stool cultures were negative for enteric pathogens; however, cultures were not obtained until the eighth hospital day and after antibiotic therapy. Extensive investigation failed to identify another cause for the diarrheal illness or HUS in our patients. Indirect immunofluorescent antibody titers for C jejuni were 1:32 and 1:16 for the mother, and daughter, respectively. An asymptomatic 9-month-old son has C jenuni isolated from his stool and had an immunofluorescent antibody titer of 1:64. Three other family members were asymptomatic, stool-culture negative, and had immunofluorescent antibody titer ≤ 1:4. The suspectibility to develop HUS following an enteric antigenic stimulus is illustrated by the patients presented. The need for systematic investigation of all HUS cases for potential susceptibility markers, as well as an exhaustive etiology search, is emphasized.

Original languageEnglish (US)
Pages (from-to)253-256
Number of pages4
Issue number2
StatePublished - 1983

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


Dive into the research topics of 'Campylobacter jejuni-associated hemolytic-uremic syndrome in a mother and daughter'. Together they form a unique fingerprint.

Cite this