@article{1aa86ce3e0d24f9ca16fcb818abdc2df,
title = "Canadian association of general surgeons and American college of surgeons evidence based reviews in surgery. 21. the risk of surgical site infection is reduced with perioperative oxygen",
abstract = "Objective: Does supplemental perioperative oxygen reduce the risk of surgical wound infection after colorectal surgery? Design: Randomized controlled trial. Setting: Multicentre trial that included 14 hospitals in Spain. Patients: 300 patients aged 18-80 years who underwent elective colorectal resection. Patients who had surgery performed laparoscopically or who had minor colon surgery were excluded. Intervention: Patients were randomly allocated to either 30% or 80% fraction of inspired oxygen (FiO2) intraoperatively and for 6 hours postoperatively. Anesthetic treatment and antibiotic administration were standardized. Main Outcome Measure: Surgical site infection (SSI) as defined by the Center for Disease Control. Results: SSI occurred in 35 of 143 patients (24.4%) who were administered 30% Fio2 and in 22 of 148 patients (14.9%) who were administered 80% FiO2 (p = 0.04). The risk of SSI was 39% lower in the 80% group (relative risk [RR], 0.61; 95% confidence interval [CI], 0.38-0.98) versus the 30% FiO2 group. Conclusions: Patients receiving supplemental oxygen have a significant reduction in risk of surgical site infection.",
author = "Karen Brasel and Donna McRitchie and Patch Dellinger and Barkun, {J. S.T.} and T. Cogbill and S. Cutter and Fitzgerald, {G. W.N.} and Henteleff, {H. J.A.} and Kirkpatrick, {A. W.} and S. Latosinsky and A. Macleon and MacRae, {H. M.} and Mastracci, {T. M.} and McLeod, {R. S.} and Neumayer, {L. A.} and S. Smith and Taylor, {M. C.} and McKenzie, {M. E.}",
note = "Funding Information: The Canadian Association of General Surgeons and the American College of Surgeons jointly sponsor a program entitled “Evidence Based Reviews in Surgery (EBRS),” which is supported by an educational grant from ETHICON and ETHICON ENDO SURGERY, both units of Johnson & Johnson Medical Products, a division of Johnson & Johnson, and ETHICON INC. and ETHICON ENDO-SURGERY, INC. divisions of Johnson & Johnson Inc. The primary objective of this initiative is to help practising surgeons improve their critical appraisal skills. During the academic year, 8 clinical articles are chosen for review and discussion. They are selected not only for their clinical relevance to general surgeons but also because they cover a spectrum of issues important to surgeons; for example, causation or risk factors for disease, natural history or prognosis of disease, how to quantify disease (measurement issues), diagnostic tests and the early diagnosis of disease and the effectiveness of treatment. A methodological article is supplied that guides the reader in critical appraisal of the clinical article. Both methodological and clinical reviews of the article are performed by experts in the relevant areas and posted on the EBRS Web site. As well, a listserv discussion is held where participants can discuss the monthly article. Members of the Canadian Association of General Surgeons and the American College of Surgeons can access Evidence Based Reviews in Surgery through the Canadian Association of General Surgeons Web site ( www.cags-accg.ca ) or the American College of Surgeons Web site ( www.facs.org ). All journal articles and reviews are available electronically through the EBRS Web site. We also have a library of past articles and reviews that can be accessed at any time. Surgeons who participate in the monthly packages can obtain Royal College of Physicians and Surgeons of Canada Maintenance of Certification credits and/or continuing medical education credits for the current article only by reading the monthly articles, participating in the listserv discussion, completing the monthly online evaluation and answering the online multiple choice questionnaire. For further information about EBRS, the reader is directed to the CAGS or ACS Web site or should email the administrator, Marg McKenzie, at mmckenzie@mtsinai.on.ca . ",
year = "2007",
month = jun,
language = "English (US)",
volume = "50",
pages = "214--216",
journal = "Canadian Journal of Surgery",
issn = "0008-428X",
publisher = "Canadian Medical Association",
number = "3",
}