Cardiac Computed Tomography in Cardio-Oncology: JACC: CardioOncology Primer

Juan C. Lopez-Mattei, Eric H. Yang, Maros Ferencik, Lauren A. Baldassarre, Susan Dent, Matthew J. Budoff

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations


Cancer patients and survivors have elevated cardiovascular risk when compared with noncancer patients. Cardio-oncology has emerged as a new subspecialty to comanage and address cardiovascular complications in cancer patients such as heart failure, atherosclerotic cardiovascular disease (ASCVD), valvular heart disease, pericardial disease, and arrhythmias. Cardiac computed tomography (CT) can be helpful in identifying both clinical and subclinical ASCVD in cancer patients and survivors. Radiation therapy treatment planning CT scans and cancer staging/re-staging imaging studies can quantify calcium scores which can identify pre-existing subclinical ASCVD. Cardiac CT can be helpful in the evaluation of cardiac tumors and pericardial diseases, especially in patients who cannot tolerate or have a contraindication to cardiac magnetic resonance. In this review, we describe the optimal utilization of cardiac CT in cancer patients, including risk assessment for ASCVD and identification of cancer treatment-related cardiovascular toxicity.

Original languageEnglish (US)
Pages (from-to)635-649
Number of pages15
JournalJACC: CardioOncology
Issue number5
StatePublished - Dec 2021


  • atherosclerotic cardiovascular disease
  • calcium score cardio-oncology
  • carcinoid syndrome
  • cardiotoxicity
  • cardiovascular computed tomography
  • radiation therapy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Oncology


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