Cariostasis by moderate doses of selenium in the rat model

Jimi Britton, Thomas R. Shearer, Del J. Desart

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The purpose of this study was to measure the effect of dietary seienium present during tooth development on dental caries. Ten-day pregnant rats received either distilied drinking water or water containing 0.8 ppm or 2.4 ppm selenium, as sodium selenite or seienomethionine, until the pups were weaned. Buccal caries were measured in the pups after being fed a MiT -200 diet for 7 wk. Moderate levels (0.8 ppm) of deveiopmental selenium significantly reduced caries in male rats when compared to control rats or to rats receiving high levels of selenium (2.4 ppm). The results indicated that moderate doses of selenium were cariostatic.

Original languageEnglish (US)
Pages (from-to)74-76
Number of pages3
JournalArchives of Environmental Health
Issue number2
StatePublished - Mar 1980
Externally publishedYes

ASJC Scopus subject areas

  • Environmental Chemistry
  • General Environmental Science
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


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