TY - JOUR
T1 - Case Report
T2 - Yellow Fever Vaccine-Associated Neurotropic Disease and Associated MRI, EEG, and CSF Findings
AU - Cohen, Michelle
AU - Nguyen, Madeline
AU - Nix, Chad D.
AU - Case, Brendan
AU - Nickerson, Joshua P.
AU - Bernard, Jacqueline
AU - Durrant, Julia
AU - Safarpour, Delaram
AU - Tucker, Tarvez
AU - Vagnerova, Kamila
AU - Messer, William B.
N1 - Publisher Copyright:
Copyright © 2022 Cohen, Nguyen, Nix, Case, Nickerson, Bernard, Durrant, Safarpour, Tucker, Vagnerova and Messer.
PY - 2022/2/18
Y1 - 2022/2/18
N2 - Yellow fever vaccine-associated neurotropic disease (YEL-AND) is a rare and serious complication following vaccination with the 17D live attenuated yellow fever vaccine. Cases of YEL-AND have presented as acute inflammatory demyelinating polyneuropathy, acute disseminated encephalomyelitis, and meningoencephalitis. To date, intracranial imaging of the progression and resolution of this disease has been minimally depicted in the literature. We present the case of a 67-year-old woman who developed YEL-AND following vaccination. Her diagnosis was complicated by imaging findings consistent with variant Creutzfeldt Jakob Disease. Her clinical history and the progression of her intracranial imaging is discussed in this case report.
AB - Yellow fever vaccine-associated neurotropic disease (YEL-AND) is a rare and serious complication following vaccination with the 17D live attenuated yellow fever vaccine. Cases of YEL-AND have presented as acute inflammatory demyelinating polyneuropathy, acute disseminated encephalomyelitis, and meningoencephalitis. To date, intracranial imaging of the progression and resolution of this disease has been minimally depicted in the literature. We present the case of a 67-year-old woman who developed YEL-AND following vaccination. Her diagnosis was complicated by imaging findings consistent with variant Creutzfeldt Jakob Disease. Her clinical history and the progression of her intracranial imaging is discussed in this case report.
KW - Creutzfeldt-Jakob Disease
KW - autoimmune encephalitis
KW - post-infectious parkinsonism
KW - vaccine adverse event
KW - yellow fever associated neurotropic disease
KW - yellow fever vaccine
KW - yellow fever virus
UR - http://www.scopus.com/inward/record.url?scp=85127185900&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85127185900&partnerID=8YFLogxK
U2 - 10.3389/fneur.2021.779014
DO - 10.3389/fneur.2021.779014
M3 - Article
AN - SCOPUS:85127185900
SN - 1664-2295
VL - 12
JO - Frontiers in Neurology
JF - Frontiers in Neurology
M1 - 779014
ER -