Cellular mechanisms of baroreceptor integration at the nucleus tractus solitarius

M. C. Andresen; M. W. Doyle; Y. H. Jin; T. W. Bailey

doi:10.1111/j.1749-6632.2001.tb03672.x

Cellular mechanisms of baroreceptor integration at the nucleus tractus solitarius

M. C. Andresen, M. W. Doyle, Y. H. Jin, T. W. Bailey

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

The autonomic nervous system makes important contributions to the homeostatic regulation of the heart and blood vessels through arterial baroreflexes, and yet our understanding of the central nervous system mechanisms is limited. The sensory synapse of baroreceptors in the nucleus tractus solitarius (NTS) is unique because its participation is obligatory in the baroreflex. Here we describe experiments targeting this synapse to provide greater understanding of the cellular mechanisms at the earliest stages of the baroreflex. Our approach utilizes electrophysiology, pharmacology, and anatomical tracers to identify and evaluate key elements of the sensory information processing in NTS.

Original language	English (US)
Pages (from-to)	132-141
Number of pages	10
Journal	Annals of the New York Academy of Sciences
Volume	940
DOIs	https://doi.org/10.1111/j.1749-6632.2001.tb03672.x
State	Published - 2001
Externally published	Yes

Keywords

Baroreceptor
Baroreflex
Glutamate
Nucleus of the solitary tract
Synaptic processing
Visceral sensory

ASJC Scopus subject areas

Neuroscience(all)
Biochemistry, Genetics and Molecular Biology(all)
History and Philosophy of Science

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10.1111/j.1749-6632.2001.tb03672.x

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title = "Cellular mechanisms of baroreceptor integration at the nucleus tractus solitarius",

abstract = "The autonomic nervous system makes important contributions to the homeostatic regulation of the heart and blood vessels through arterial baroreflexes, and yet our understanding of the central nervous system mechanisms is limited. The sensory synapse of baroreceptors in the nucleus tractus solitarius (NTS) is unique because its participation is obligatory in the baroreflex. Here we describe experiments targeting this synapse to provide greater understanding of the cellular mechanisms at the earliest stages of the baroreflex. Our approach utilizes electrophysiology, pharmacology, and anatomical tracers to identify and evaluate key elements of the sensory information processing in NTS.",

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AU - Andresen, M. C.

AU - Doyle, M. W.

AU - Jin, Y. H.

AU - Bailey, T. W.

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AB - The autonomic nervous system makes important contributions to the homeostatic regulation of the heart and blood vessels through arterial baroreflexes, and yet our understanding of the central nervous system mechanisms is limited. The sensory synapse of baroreceptors in the nucleus tractus solitarius (NTS) is unique because its participation is obligatory in the baroreflex. Here we describe experiments targeting this synapse to provide greater understanding of the cellular mechanisms at the earliest stages of the baroreflex. Our approach utilizes electrophysiology, pharmacology, and anatomical tracers to identify and evaluate key elements of the sensory information processing in NTS.

KW - Baroreceptor

KW - Baroreflex

KW - Glutamate

KW - Nucleus of the solitary tract

KW - Synaptic processing

KW - Visceral sensory

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Cellular mechanisms of baroreceptor integration at the nucleus tractus solitarius

Abstract

Keywords

ASJC Scopus subject areas

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