Characterization and functional restoration of a potassium channel Kir6.2 pore mutation identified in congenital hyperinsulinism

Keyphrases

• Potassium Channel 100%
• Kir6.2 100%
• Congenital Hyperinsulinism 100%
• Functional Restoration 100%
• Glycine 50%
• KATP Channel 33%
• Insulin Secretion 33%
• Inward Rectifier Potassium Channel 33%
• Aspartate 33%
• Ion Conduction 33%
• Arginine 16%
• Polyamines 16%
• Conductance 16%
• Helix 16%
• Surface Expression 16%
• Missense 16%
• Potassium Current 16%
• Channel Gating 16%
• ATP-sensitive Potassium Channel 16%
• Pancreatic Cells 16%
• Homomeric 16%
• Membrane Potential 16%
• SUR1 16%
• Transmembrane Helix 16%
• Chemical Interaction 16%
• Asparagine 16%
• COS Cells 16%
• Ion Gate 16%
• Pore Lining 16%

Biochemistry, Genetics and Molecular Biology

• Potassium Channel 100%
• Kir6.2 100%
• Congenital Hyperinsulinism 100%
• Adenosine Triphosphate 33%
• ATP-Sensitive Potassium Channel 33%
• Insulin Release 33%
• Wild Type 16%
• Surface Property 16%
• Conductance 16%
• Arginine 16%
• Channel Gating 16%
• Missense 16%
• Membrane Potential 16%
• Sulfonylurea Receptor 16%
• Potassium Current 16%
• Inward-Rectifier Potassium Ion Channel 16%
• COS Cells 16%
• Asparagine 16%
• Chemical Interaction 16%