Chemoenzymatic enrichment of phosphotyrosine-containing peptides

Shuwei Li; Dexing Zeng

doi:10.1002/anie.200700633

Chemoenzymatic enrichment of phosphotyrosine-containing peptides

Shuwei Li, Dexing Zeng

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

(Chemical Equation Presented) Change the Tyr: A tyrosinase-assisted chemoenzymatic method was used to modify and enrich phosphotyrosine-containing peptides from a peptide mixture. This approach could be used to study protein tyrosine phosphorylation, and represents a promising alternative to immunoaffinity purification by using antiphosphotyrosine antibodies.

Original language	English (US)
Pages (from-to)	4751-4753
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	46
Issue number	25
DOIs	https://doi.org/10.1002/anie.200700633
State	Published - 2007
Externally published	Yes

Keywords

Biotin
Mass spectrometry
Proteomics
Tyrosinases
Tyrosine phosphorylation

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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10.1002/anie.200700633

Cite this

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title = "Chemoenzymatic enrichment of phosphotyrosine-containing peptides",

abstract = "(Chemical Equation Presented) Change the Tyr: A tyrosinase-assisted chemoenzymatic method was used to modify and enrich phosphotyrosine-containing peptides from a peptide mixture. This approach could be used to study protein tyrosine phosphorylation, and represents a promising alternative to immunoaffinity purification by using antiphosphotyrosine antibodies.",

keywords = "Biotin, Mass spectrometry, Proteomics, Tyrosinases, Tyrosine phosphorylation",

author = "Shuwei Li and Dexing Zeng",

year = "2007",

doi = "10.1002/anie.200700633",

language = "English (US)",

volume = "46",

pages = "4751--4753",

journal = "Angewandte Chemie - International Edition",

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T1 - Chemoenzymatic enrichment of phosphotyrosine-containing peptides

AU - Li, Shuwei

AU - Zeng, Dexing

PY - 2007

Y1 - 2007

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AB - (Chemical Equation Presented) Change the Tyr: A tyrosinase-assisted chemoenzymatic method was used to modify and enrich phosphotyrosine-containing peptides from a peptide mixture. This approach could be used to study protein tyrosine phosphorylation, and represents a promising alternative to immunoaffinity purification by using antiphosphotyrosine antibodies.

KW - Biotin

KW - Mass spectrometry

KW - Proteomics

KW - Tyrosinases

KW - Tyrosine phosphorylation

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U2 - 10.1002/anie.200700633

DO - 10.1002/anie.200700633

M3 - Article

C2 - 17506057

AN - SCOPUS:34347230512

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

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ER -

Chemoenzymatic enrichment of phosphotyrosine-containing peptides

Abstract

Keywords

ASJC Scopus subject areas

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