TY - JOUR
T1 - Chromosome heteromorphism analysis in cases of disputed paternity
AU - Olson, S. B.
AU - Magenis, R. E.
AU - Rowe, S. I.
AU - Lovrien, E. W.
PY - 1983
Y1 - 1983
N2 - Blood test results, using standard procedures, failed to exclude the alleged father as the biological father of a child in a case of disputed paternity. Using 21 different systems, the probability of exclusion for the man was 98.19%, and the probability of paternity was only 93.90% with a paternity index of 15.48. Chromosome heteromorphisms of all three individuals were studied. By comparison of fluorescent markers of chromsomes 13, 14, 15, 21, and 22, the child was shown to inherit one homologue of each of these chromosomes from the mother, but none were like the heteromorphisms of the alleged father. This excluded him as the biological father.
AB - Blood test results, using standard procedures, failed to exclude the alleged father as the biological father of a child in a case of disputed paternity. Using 21 different systems, the probability of exclusion for the man was 98.19%, and the probability of paternity was only 93.90% with a paternity index of 15.48. Chromosome heteromorphisms of all three individuals were studied. By comparison of fluorescent markers of chromsomes 13, 14, 15, 21, and 22, the child was shown to inherit one homologue of each of these chromosomes from the mother, but none were like the heteromorphisms of the alleged father. This excluded him as the biological father.
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U2 - 10.1002/ajmg.1320150106
DO - 10.1002/ajmg.1320150106
M3 - Article
C2 - 6574701
AN - SCOPUS:0020567544
SN - 0148-7299
VL - 15
SP - 47
EP - 55
JO - American Journal of Medical Genetics
JF - American Journal of Medical Genetics
IS - 1
ER -