TY - JOUR
T1 - Chronic kidney diseases in agricultural communities
T2 - report from a workshop
AU - Mendley, Susan R.
AU - Levin, Adeera
AU - Correa-Rotter, Ricardo
AU - Joubert, Bonnie R.
AU - Whelan, Elizabeth A.
AU - Curwin, Brian
AU - Koritzinsky, Erik H.
AU - Gaughan, Denise M.
AU - Kimmel, Paul L.
AU - Anand, Shuchi
AU - Ordunez, Pedro
AU - Reveiz, Ludovic
AU - Rohlman, Diane S.
AU - Scammell, Madeleine K.
AU - Wright, Robert O.
AU - Star, Robert A.
N1 - Funding Information:
This workshop was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health (NIH). The following persons are members of the faculty and organizing committee: Kevin Abbott, Division of Kidney, Urologic, and Hematologic Diseases, NIDDK, NIH; Liz Amos, National Library of Medicine, NIH; Shuchi Anand, Stanford University; Kate Applebaum, George Washington University; John Balbus, NIEHS–World Health Organization Collaborating Centre for Environmental Health Sciences, NIEHS, NIH; Ricardo Correa-Rotter, Instituto Nacional de Ciencas Médicas y Nutrición Salvador Zubirán (Mexico); Brian Curwin, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention; Marc De Broe, University of Antwerp; José Escamilla, Pan American Health Organization; David Friedman, Harvard Medical School; Denise M. Gaughan, Division of Kidney, Urologic, and Hematologic Diseases, NIDDK, NIH; Jason Glaser, La Isla Network; Arthur Grollman, Stony Brook University School of Medicine; David Sheikh Hamad, Baylor College of Medicine; Bonnie R. Joubert, Population Health Branch, NIEHS, NIH; Paul Kimmel, Division of Kidney, Urologic, and Hematologic Diseases, NIDDK, NIH; Erik H. Koritzinsky, Division of Kidney, Urologic, and Hematologic Diseases, NIDDK, NIH; Ty Lawson, NIEHS–World Health Organization Collaborating Centre for Environmental Health Sciences, NIEHS, NIH; Adeera Levin, University of British Columbia (Canada); Susan Mendley, Division of Kidney, Urologic, and Hematologic Diseases, NIDDK, NIH; Kathleen Michels, Division of International Research and Training, Fogarty International Center, NIH; Murray Mittelman, Harvard University; Ana Navas-Acien, Columbia University; Geoff Plumlee, US Geological Survey; Ludovic Reveiz, Pan American Health Organization; Diane Rohlman, University of Iowa; Pierre Rollin, Viral Special Pathogens Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention; Carla Saenz, Pan American Health Organization; Dale Sandler, Epidemiology Branch, NIEHS, NIH; Rajiv Saran, University of Michigan; Madeleine Scammell, Boston University; Carol Shreffler, Exposure, Response, and Technology Branch, NIEHS, NIH; William Suk, Hazardous Substances Research Branch, NIEHS, NIH; Brittany Trottier, Hazardous Substances Research Branch, NIEHS, NIH; Elizabeth A. Whelan, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention; Robert Wright, Icahn School of Medicine at Mount Sinai; and Yining Xie, Division of Kidney, Urologic, and Hematologic Diseases, NIDDK, NIH. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, or the Pan American Health Organization.
Funding Information:
This workshop was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health (NIH). The following persons are members of the faculty and organizing committee: Kevin Abbott, Division of Kidney, Urologic, and Hematologic Diseases, NIDDK, NIH; Liz Amos, National Library of Medicine, NIH; Shuchi Anand, Stanford University; Kate Applebaum, George Washington University; John Balbus, NIEHS–World Health Organization Collaborating Centre for Environmental Health Sciences, NIEHS, NIH; Ricardo Correa-Rotter, Instituto Nacional de Ciencas Médicas y Nutrición Salvador Zubirán (Mexico); Brian Curwin, National Institute for Occupational Safety and Health, Centrs for Disease Control and Prevention; Marc De Broe, University of Antwerp; José Escamilla, Pan American Health Organization; David Friedman, Harvard Medical School; Denise M. Gaughan, Division of Kidney, Urologic, and Hematologic Diseases, NIDDK, NIH; Jason Glaser, La Isla Network; Arthur Grollman, Stony Brook University School of Medicine; David Sheikh Hamad, Baylor College of Medicine; Bonnie R. Joubert, Population Health Branch, NIEHS, NIH; Paul Kimmel, Division of Kidney, Urologic, and Hematologic Diseases, NIDDK, NIH; Erik H. Koritzinsky, Division of Kidney, Urologic, and Hematologic Diseases, NIDDK, NIH; Ty Lawson, NIEHS–World Health Organization Collaborating Centre for Environmental Health Sciences, NIEHS, NIH; Adeera Levin, University of British Columbia (Canada); Susan Mendley, Division of Kidney, Urologic, and Hematologic Diseases, NIDDK, NIH; Kathleen Michels, Division of International Research and Training, Fogarty International Center, NIH; Murray Mittelman, Harvard University; Ana Navas-Acien, Columbia University; Geoff Plumlee, US Geological Survey; Ludovic Reveiz, Pan American Health Organization; Diane Rohlman, University of Iowa; Pierre Rollin, Viral Special Pathogens Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention; Carla Saenz, Pan American Health Organization; Dale Sandler, Epidemiology Branch, NIEHS, NIH; Rajiv Saran, University of Michigan; Madeleine Scammell, Boston University; Carol Shreffler, Exposure, Response, and Technology Branch, NIEHS, NIH; William Suk, Hazardous Substances Research Branch, NIEHS, NIH; Brittany Trottier, Hazardous Substances Research Branch, NIEHS, NIH; Elizabeth A. Whelan, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention; Robert Wright, Icahn School of Medicine at Mount Sinai; and Yining Xie, Division of Kidney, Urologic, and Hematologic Diseases, NIDDK, NIH.
Publisher Copyright:
© 2019
PY - 2019/11
Y1 - 2019/11
N2 - In June 2018, the National Institute of Diabetes and Digestive and Kidney Diseases and the National Institute of Environmental Health Sciences sponsored a workshop to identify research gaps in an increasingly common form of chronic kidney disease in agricultural communities, often termed “CKDu.” The organizers invited a broad range of experts who provided diverse expertise and perspectives, many of whom had never addressed this particular epidemic. Discussion was focused around selected topics, including identifying and mitigating barriers to research in CKDu, creating a case definition, and defining common data elements. All hypotheses regarding etiology were entertained, and meeting participants discussed potential research strategies, choices in study design, and novel tools that may prove useful in this disease. Achievements of the workshop included robust cross-disciplinary discussion and preliminary planning of research goals and design. Specific challenges in implementing basic and clinical research and interventions in low- and middle-income countries were recognized. A balanced approach to leveraging local resources and capacity building without overreaching was emphasized.
AB - In June 2018, the National Institute of Diabetes and Digestive and Kidney Diseases and the National Institute of Environmental Health Sciences sponsored a workshop to identify research gaps in an increasingly common form of chronic kidney disease in agricultural communities, often termed “CKDu.” The organizers invited a broad range of experts who provided diverse expertise and perspectives, many of whom had never addressed this particular epidemic. Discussion was focused around selected topics, including identifying and mitigating barriers to research in CKDu, creating a case definition, and defining common data elements. All hypotheses regarding etiology were entertained, and meeting participants discussed potential research strategies, choices in study design, and novel tools that may prove useful in this disease. Achievements of the workshop included robust cross-disciplinary discussion and preliminary planning of research goals and design. Specific challenges in implementing basic and clinical research and interventions in low- and middle-income countries were recognized. A balanced approach to leveraging local resources and capacity building without overreaching was emphasized.
KW - Mesoamerican nephropathy
KW - chronic interstitial nephritis of agricultural communities
KW - chronic kidney disease of uncertain/nontraditional etiology
KW - environmental exposure
KW - kidney disease of unknown cause in agricultural laborers
KW - low- and middle-income countries
KW - tubulointerstitial
UR - http://www.scopus.com/inward/record.url?scp=85072598712&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85072598712&partnerID=8YFLogxK
U2 - 10.1016/j.kint.2019.06.024
DO - 10.1016/j.kint.2019.06.024
M3 - Article
C2 - 31563333
AN - SCOPUS:85072598712
SN - 0085-2538
VL - 96
SP - 1071
EP - 1076
JO - Kidney International
JF - Kidney International
IS - 5
ER -