Chronic myeloid leukemia mimicking idiopathic intracranial hypertension

A 27-year-old woman presented with headache and bilateral optic disc edema. Neuroimaging was negative for an intracranial mass. An initial lumbar puncture showed elevated intracranial pressure, but normal cerebrospinal fluid contents. A diagnosis of 'idiopathic intracranial hypertension' was made. Ophthalmoscopy subsequently disclosed bilateral optic disc edema and multifocal retinal hemorrhages with white centers (Roth spots). Complete blood count and bone marrow examination confirmed the diagnosis of chronic myeloid leukemia. The diagnosis of idiopathic intracranial hypertension in patients should be suspect in patients who do not fit the typical profile (e.g., thin, elderly, or male patients or patients with unusual fundus findings).