Chronic sinonasal disease in patients with inflammatory bowel disease

David T. Book, Timothy L. Smith, Justin P. McNamar, Kia Saeian, David G. Binion, Robert J. Toohill

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Background: The objective of this study was to explore the possible relationship between inflammatory bowel disease (IBD) and chronic sinonasal disease. Methods: A cross-sectional study was undertaken of 241 patients with Crohn's disease (CD) or ulcerative colitis from a tertiary medical center IBD clinic. Patient demographic data and information regarding IBD diagnosis and management, sinonasal disease diagnosis and management, and complications related to these diagnoses were gathered by retrospective chart review and a standardized patient survey. Results: One hundred sixty surveys (67%) were returned and analyzed. Overall, 48% of patients with IBD reported chronic sinonasal disease symptoms. Patients with CD had a higher prevalence of sinonasal disease than patients with ulcerative colitis (53% versus 32%; p < 0.02). The subgroup of CD patients with obstructive bowel complications had the highest prevalence of sinonasal disease (68% versus 27%; p = < 0.001), with 23% reporting chronic rhinosinusitis, 13% reporting chronic rhinitis, and an additional 32% reporting chronic nasal or sinus symptoms. Conclusion: The prevalence of chronic sinonasal disease is elevated in patients with IBD, occurring in approximately one-half of patients followed at a tertiary IBD center. Patients with CD experiencing obstructive complications had significantly increased rates of sinonasal disease. The relationship between chronic sinonasal disease and obstructive CD is not defined, but several hypotheses are generated.

Original languageEnglish (US)
Pages (from-to)87-90
Number of pages4
JournalAmerican Journal of Rhinology
Issue number2
StatePublished - 2003
Externally publishedYes

ASJC Scopus subject areas

  • Otorhinolaryngology


Dive into the research topics of 'Chronic sinonasal disease in patients with inflammatory bowel disease'. Together they form a unique fingerprint.

Cite this