@article{f2dd7c01cc904958a4ad3ee16ecdec3a,
title = "Circadian rhythm in negative affect: Implications for mood disorders",
abstract = "In humans, there is an endogenous, near 24-h (i.e., circadian) variation in mood with the best mood occurring during the circadian day and the worst mood occurring during the circadian night. Only positive affect, and not negative affect, has been shown to contribute to this circadian rhythm. We discovered a sharp circadian peak in negative affect during the circadian night coincident with a circadian trough in positive affect. These findings may help explain the association of depression with insomnia, the increased risk of suicide with nocturnal wakefulness, and the correlation between circadian misalignment and symptom severity in Major Depressive Disorder.",
keywords = "Circadian, Mood disorders, Sleep",
author = "Emens, {Jonathan S.} and Berman, {Alec M.} and Thosar, {Saurabh S.} and Butler, {Matthew P.} and Roberts, {Sally A.} and Clemons, {Noal A.} and Herzig, {Maya X.} and McHill, {Andrew W.} and Miki Morimoto and Bowles, {Nicole P.} and Shea, {Steven A.}",
note = "Funding Information: We wish to acknowledge the study participants and the Oregon Clinical and Translational Research Institute nursing staff. This work was supported by the National Institutes of Health grants R01-HL125893, R01-HL142064, R01-HL140577, F32-HL131308, KL2-TR002370, and UL1-TR000128; NSBRI NCC 9-58; American Sleep Medicine Foundation; Ford Foundation; and the Oregon Institute of Occupational Health Sciences. Funding Information: This work was supported by the National Institutes of Health grants R01-HL125893 , R01-HL142064 , R01-HL140577 , F32-HL131308 , KL2-TR002370 , and UL1-TR000128 ; NSBRI NCC 9-58 ; American Sleep Medicine Foundation ; Ford Foundation ; and the Oregon Institute of Occupational Health Sciences . Publisher Copyright: {\textcopyright} 2020",
year = "2020",
month = nov,
doi = "10.1016/j.psychres.2020.113337",
language = "English (US)",
volume = "293",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",
}