TY - JOUR
T1 - Clinical presentation and outcomes of adults with bicuspid aortic valves
T2 - 2020 update
AU - Yang, Li Tan
AU - Tribouilloy, Christophe
AU - Masri, Ahmad
AU - Bax, Jeroen J.
AU - Delgado, Victoria
AU - Girdauskas, Evaldas
AU - Evangelista, Arturo
AU - Sundt, Thoralf M.
AU - Svensson, Lars G.
AU - Enriquez-Sarano, Maurice
AU - Michelena, Hector I.
N1 - Publisher Copyright:
© 2020 Elsevier Inc.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - The congenital bicuspid aortic valve (BAV) is a heterogeneous condition that is better understood considering 3 types of valvulo-aortopathy presentations: A typical-presentation valvulo-aortopathy, a complex-presentation valvulo-aortopathy and an uncomplicated/undiagnosed-presentation. The burden of BAV-related complications has been elucidated in patients with the typical-presentation valvulo-aortopathy and is discussed in this review. These patients enjoy an overall normal expected long-term survival as long as complications are identified and treated in a timely manner. This notion and the fact that the most dreaded complications (infective endocarditis and aortic dissection) are infrequent, represent important reassuring points for the BAV patient. Common complications such as valve dysfunction and aorta dilatation must be the subject of focused research in prevention and treatment. Conversely, BAV patients with complex-presentation valvulo-artopathy, as well as typical valvulo-aortopathy BAV patients who are older, with advanced valvular dysfunction, and possible late-referral to specialized care, may incur a survival penalty as compared to the general population. An evidence-based discussion of these concepts is provided in this review.
AB - The congenital bicuspid aortic valve (BAV) is a heterogeneous condition that is better understood considering 3 types of valvulo-aortopathy presentations: A typical-presentation valvulo-aortopathy, a complex-presentation valvulo-aortopathy and an uncomplicated/undiagnosed-presentation. The burden of BAV-related complications has been elucidated in patients with the typical-presentation valvulo-aortopathy and is discussed in this review. These patients enjoy an overall normal expected long-term survival as long as complications are identified and treated in a timely manner. This notion and the fact that the most dreaded complications (infective endocarditis and aortic dissection) are infrequent, represent important reassuring points for the BAV patient. Common complications such as valve dysfunction and aorta dilatation must be the subject of focused research in prevention and treatment. Conversely, BAV patients with complex-presentation valvulo-artopathy, as well as typical valvulo-aortopathy BAV patients who are older, with advanced valvular dysfunction, and possible late-referral to specialized care, may incur a survival penalty as compared to the general population. An evidence-based discussion of these concepts is provided in this review.
KW - Bicuspid aortic valve
KW - Clinical history
KW - Complication
KW - Valve dysfunction
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U2 - 10.1016/j.pcad.2020.05.010
DO - 10.1016/j.pcad.2020.05.010
M3 - Review article
C2 - 32485187
AN - SCOPUS:85086034406
SN - 0033-0620
VL - 63
SP - 434
EP - 441
JO - Progress in Cardiovascular Diseases
JF - Progress in Cardiovascular Diseases
IS - 4
ER -