Coisogenic Strain

Research output: Chapter in Book/Report/Conference proceedingChapter


A coisogenic pair of strains differs only at a single genetic locus. A coisogenic strain can occur as the result of a random mutation, or can be created using genetic engineering, chemical mutagenesis, or irradiation. Comparison of a coisogenic pair of strains is a powerful method for detecting the effects of a single gene.

Original languageEnglish (US)
Title of host publicationBrenner's Encyclopedia of Genetics
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Number of pages1
ISBN (Electronic)9780080961569
ISBN (Print)9780123749840
StatePublished - Feb 27 2013


  • Allele
  • Chemical mutagenesis
  • Congenic strain
  • Embryonic cells
  • Genetic engineering
  • Inbred strain
  • Irradiation
  • Random mutagenesis
  • Single-gene mutant
  • Spontaneous mutation

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology
  • General Medicine


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