Abstract
A coisogenic pair of strains differs only at a single genetic locus. A coisogenic strain can occur as the result of a random mutation, or can be created using genetic engineering, chemical mutagenesis, or irradiation. Comparison of a coisogenic pair of strains is a powerful method for detecting the effects of a single gene.
Original language | English (US) |
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Title of host publication | Brenner's Encyclopedia of Genetics |
Subtitle of host publication | Second Edition |
Publisher | Elsevier Inc. |
Pages | 84 |
Number of pages | 1 |
ISBN (Electronic) | 9780080961569 |
ISBN (Print) | 9780123749840 |
DOIs | |
State | Published - Feb 27 2013 |
Keywords
- Allele
- Chemical mutagenesis
- Congenic strain
- Embryonic cells
- Genetic engineering
- Inbred strain
- Irradiation
- Random mutagenesis
- Single-gene mutant
- Spontaneous mutation
ASJC Scopus subject areas
- General Agricultural and Biological Sciences
- General Biochemistry, Genetics and Molecular Biology
- General Medicine