Colorectal polyposis and inherited colorectal cancer syndromes

Raphael M. Byrne, Vassiliki Liana Tsikitis

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations

Abstract

The majority of colorectal cancer (CRC) cases are sporadic, with hereditary factors contributing to approximately 35% of CRC cases. Less than 5% of CRC is associated with a known genetic syndrome. Although adenomatous polyposis syndromes, hamartomatous polyposis syndromes, and those previously classified as non-polyposis CRC syndromes are quite rare, it is important for clinicians to know the characteristics of each syndrome and to understand the differences in cancer risks between the different conditions. This information is very important when treatment and surveillance plans are formulated for each individual patient.

Original languageEnglish (US)
Pages (from-to)24-34
Number of pages11
JournalAnnals of Gastroenterology
Volume31
Issue number1
DOIs
StatePublished - 2018

Keywords

  • Adenomatous polyposis syndromes
  • Cancer risk
  • Colorectal cancer
  • Hamartomatous polyposis syndromes
  • Nonpolyposis colorectal cancer syndromes

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint

Dive into the research topics of 'Colorectal polyposis and inherited colorectal cancer syndromes'. Together they form a unique fingerprint.

Cite this