Complete nucleotide sequence of a chicken H2b histone gene

D. K. Grandy, J. D. Engel, J. B. Dodgson

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


The complete nucleotide sequence of a chicken H2b histone gene has been determined along with extensive flanking sequence both 5' and 3' from the gene. This H2b gene was isolated on λ Charon 4A-chicken DNA recombinant in which it is closely linked to two H3 histone genes. The H2b histone gene predicts a chicken H2b histone protein sequence differing in 5 of 125 amino acids from the sequence of a calf thymus H2b histone. The gene is uninterrupted and is flanked by several consensus sequences seen in many other eucaryotic genes. In particular, unlike many other histone genes it contains a 3'-AATAAA sequence usually associated with genes coding for polyadenylated mRNA.

Original languageEnglish (US)
Pages (from-to)8577-8580
Number of pages4
JournalJournal of Biological Chemistry
Issue number15
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology


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