Contralateral effects of cerebello-pontine angle exposure on human auditory brain-stem evoked potentials

Hillel Pratt, William H. Martin, John W. Schwegler

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Auditory brain-stem evoked potentials (ABEPs) were recorded during surgical procedures which exposed the cerebello-pontine angle (CPA) in humans. Recordings made with the CPA contralateral to stimulus exposed were compared with those obtained with the skin sutured at the end of surgery. Single-channel as well as 3-channel Lissajous' trajectory (3-CLT) analyses were used to evaluate the effect of the surgical exposure on ABEP. The results suggest that exposure of the CPA contralateral to the stimulated ear did not affect dipole equivalent orientation nor magnitude, but did affect timing of the recorded activity being more pronounced for segments 'd'-'e' (corresponding to waves IV-V) than for 'a'-'b' (waves I-II). The results imply that the effects of disrupting the volume conductor may have been overwhelmed by other effects, such as local temperature changes. These changes, although not associated with clinical sequella, should be accounted for when analyzing subtle quantitative changes involving surgical exposures.

Original languageEnglish (US)
Pages (from-to)153-161
Number of pages9
JournalElectroencephalography and Clinical Neurophysiology
Issue number2
StatePublished - Aug 1992
Externally publishedYes


  • Auditory brain-stem evoked potentials
  • Intraoperative monitoring
  • Signal/noise
  • Temperature effects
  • Three-channel Lissajous' trajectory
  • Volume conductor

ASJC Scopus subject areas

  • General Neuroscience
  • Clinical Neurology


Dive into the research topics of 'Contralateral effects of cerebello-pontine angle exposure on human auditory brain-stem evoked potentials'. Together they form a unique fingerprint.

Cite this