TY - JOUR
T1 - Contrast echocardiography
T2 - Current status and future directions
AU - Lindner, Jonathan R.
N1 - Funding Information:
Funding JRL is supported by grants R01-HL078610, R01-HL130046 and P51-OD011092 from the National Institutes of Health, Bethesda, Maryland, USA, and grant 14-14NSBRI1-0025 from NASA.
Publisher Copyright:
©
PY - 2021/1/1
Y1 - 2021/1/1
N2 - Contrast echocardiography is a family of ultrasound-based procedures, whereby acoustic enhancing agents, usually microbubbles, are administered by intravenous route and detected in order to improve diagnostic performance. This review describes: (1) the agents that have been designed for diagnostic imaging, (2) current clinical applications where either left ventricular opacification or microvascular perfusion imaging with myocardial contrast echocardiography have been demonstrated to provide incremental information to non-contrast echocardiography and (3) future diagnostic and therapeutic applications of contrast ultrasound that rely on unique compositional design of ultrasound-enhancing agents.
AB - Contrast echocardiography is a family of ultrasound-based procedures, whereby acoustic enhancing agents, usually microbubbles, are administered by intravenous route and detected in order to improve diagnostic performance. This review describes: (1) the agents that have been designed for diagnostic imaging, (2) current clinical applications where either left ventricular opacification or microvascular perfusion imaging with myocardial contrast echocardiography have been demonstrated to provide incremental information to non-contrast echocardiography and (3) future diagnostic and therapeutic applications of contrast ultrasound that rely on unique compositional design of ultrasound-enhancing agents.
KW - advanced cardiac imaging
KW - echocardiography
UR - http://www.scopus.com/inward/record.url?scp=85096620554&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85096620554&partnerID=8YFLogxK
U2 - 10.1136/heartjnl-2020-316662
DO - 10.1136/heartjnl-2020-316662
M3 - Review article
C2 - 33077502
AN - SCOPUS:85096620554
SN - 1355-6037
VL - 107
SP - 18
EP - 24
JO - Heart
JF - Heart
IS - 1
ER -